Lab help reading

LFG

Member
Hey all, can you help me with my test results. I’m currently on 30mg EOD of test cyp. I just changed from e3.5d to EOD 8 months ago to see if it will help me feel better. I was a little sluggish so I tried the change.

It’s been slightly better but I was tested in December and TT = 956 and FT= 182 Estradoil = 45

and now I just got them tested again, so it’s been 8 months. My TT = 1359 and FT = 261 and Estradiol = 40

No idea why my test jumped up that much.. any thoughts on this? I feel OK but I do not feel like I’m fully optimized.
 

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It’s been slightly better but I was tested in December and TT = 956 and FT= 182 Estradoil = 45

and now I just got them tested again, so it’s been 8 months. My TT = 1359 and FT = 261 and Estradiol = 40
TRT isn't a set and forget treatment, adjustments may be needed from time to time.

I feel OK but I do not feel like I’m fully optimized.
An optimized TRT protocol is only part of the equation to feeling optimal, nutrition, exercise and quality of sleep are equally as important.

You will never feel fully optimized if any of these areas of your lifestyle are lacking.
 
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I'm pretty sure at least one of the tests is fouled up. These mass spectrometry-based tests, while capable of high accuracy, are also temperamental and easy to screw up. My understanding is that the free testosterone measurement is linked to the total in this methodology. So if the total is fouled up then both results end up wrong.

It's interesting that the ratio of free to total testosterone is about the same for the two different dates. It's also telling that estradiol didn't vary much. Under the circumstances lab error is more plausible than some unusual combination of dosing errors and metabolic changes.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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