Regarding dosing, yes that could be an issue, and as with everything, people will respond differently, however I was also using a very low dose and only once a day. I may try again at some point since I have a vial just sitting there, but my main point is...why use CJC when mod-GRF should accomplish the same thing in a more natural way. Also, I seem to remember bloat being an issue with MK677 so that might be another reason to avoid the compounds that persist in the body.