Ipamorelin Dosage Discussion

On recent labs, my doctor noted my IGF-1 was on the low end, 105ng/mL (range 88-246).

He added 350 micrograms of ipamorelin per day to my current protocol, injected before bed every night. I've been trying to do a bit of research on ipamorelin, its efficacy and safety, but have come up short. There is not a lot out there on Youtube, etc.


Is anyone out there using this? What are your thoughts on it? Is it worth it or a waste of money?

Based on the search results, here are the key points about Ipamorelin dosage:

1. Typical dosage range:
- 100-300 mcg per injection[1][4][6]
- Administered 1-3 times daily[1][4][6]

2. Common dosing protocols:
- 200-300 mcg total daily dose, split into 2-3 injections[6]
- 300 mcg per day, typically administered before bed[7][8]

3. Dosing frequency:
- Daily or 5 times per week[4][8]
- Often taken at night to mimic natural growth hormone release[7][8]

4. Duration of use:
- Cycles typically last 8-12 weeks[5]
- Followed by a 4-8 week break period[5]

5. Administration:
- Given via subcutaneous injection[1][6]
- Taken on an empty stomach, at least 30-60 minutes before or after eating[1][4]

6. Personalization:
- Dosage may need to be adjusted based on individual factors like age, weight, and goals[4][5]
- It's recommended to start with a lower dose and increase gradually if needed[5]

7. Medical supervision:
- Consultation with a healthcare provider is crucial to determine the appropriate dosage[4][5]

8. Combination use:
- Often combined with CJC-1295 for synergistic effects[7]
- When combined, a typical dose might be 500 mcg Ipamorelin with 250 mcg CJC-1295[7]

It's important to note that Ipamorelin is not FDA-approved for human use, and these dosages are based on research and anecdotal reports. Always consult with a qualified healthcare professional before using any peptides.

Citations:
[1] Ipamorelin
[2] Understanding the Correct Dosage of Ipamorelin for Optimal Health Benefits
[3] Ipamorelin Overview, Dosage, and Risks — peptidesinstitute.org
[4] How Much cjc-1295 Ipamorelin Should I Take Explained by Tulsi
[5] Ipamorelin CJC 1295: Ideal Dosage for Fitness - Anti-Aging Northwest
[6] Ipamorelin Dosage Calculator and Chart | A-Z Guide
[7] Ipamorelin/CJC1295
[8] SERMORELIN/IPAMORELIN - Houston Men's Health Clinic

 

So, I wanted to do the ipamorelin cjc combo, but none of the pharmacies that Defy works with ships to California, so I had to get get one vials of Semorelin and Ipamorelin. I thought I would just stop all together after trying it but I'm seeing body definition my fat self has always wanted (I'm fit and am active and eat fairly healthy - occasional cookie or slice of cake). But the cost of $330 a month is costing too much. Do you know if there are any other alternative like Ipamorelin and MK to keep costs down?

 

So, I wanted to do the ipamorelin cjc combo, but none of the pharmacies that Defy works with ships to California, so I had to get get one vials of Semorelin and Ipamorelin. I thought I would just stop all together after trying it but I'm seeing body definition my fat self has always wanted (I'm fit and am active and eat fairly healthy - occasional cookie or slice of cake). But the cost of $330 a month is costing too much. Do you know if there are any other alternative like Ipamorelin and MK to keep costs down?

Personally, I would go with Mk677 - Ibutamoren. I had far better igf1 increases with that vs IPam. It’s about $3/pill from Defy but you only need to take it every other day to get great results. So, ~$100 / month or less for 12.5 mg EOD bumped my igf1 from 100 to over 160.

 

Personally, I would go with Mk677 - Ibutamoren. I had far better igf1 increases with that vs IPam. It’s about $3/pill from Defy but you only need to take it every other day to get great results. So, ~$100 / month or less for 12.5 mg EOD bumped my igf1 from 100 to over 160.

I’ll try it out. Will report back here

 

ipamorelin

www.excelmale.com

 

I like it also. I have also tried a higher dose of 2 mg per day but I had a lot of water retention. Now on 0.5 mg per day. No issues.

Do you use it solo or with a y CJC ?

 

GH will always be more effective - the same way exogenous testosterone typically raises Test levels more than HCG. But.... Ipam is way cheaper and does not cause any desensitization or shutting down your own production. And it works very well.

Would the same be true with CJC 1295/Ipamorelin combo?

 

Yes. Only Semorelin, to my knowledge, has some desensitization effects. Cjc /Ipamorelin can be run long term. So can MK677.

 

wait, really? I've been doing 3 months on 2-3 weeks off like a silly person just in case, but it does make sense that maybe it wouldn't desensitize. Is there data to back this up or other anecdotes? I know the nature of peptides means we won't see large clinical trials.

I run ipamorelin + cjc w/o dac + bpc 157 + bp500. Life changing and cycling off doesn't bother me that much but I do feel the difference.

 

Still running it. I did not get any additional fat loss after that initial period. I also added a low dose of nandrolone from my doctor. The combination of the two accelerated healing, even cartilage damage.

Jim, how many Mg's of Nandrolone are running/wk?

 

Jim, how many Mg's of Nandrolone are running/wk?

I had beeen running 120mg Nandrolone for 6 months. I came off for 6 weeks and now just went back on - taking 50mg every 5 days with trt shot. I also add 50mg primabolin which also has some collagen synthesis benefits. I feel better already after just adding back the nandrolone 2 weeks ago

 

Thank you.

Tesamorelin is approved for decreasing HIV-related abdominal fat (brand name Egrifta). It decreased visceral fat by 20% in 2/3 of subjects after 26 weeks of daily injections of 2 mg. These patients were not on special diet or exercise.

Here is a document from the FDA: https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022505s000lbl.pdf

Since Imaporelin is "better" do you think it will have similar visceral fat burning qualities?

 

Since Imaporelin is "better" do you think it will have similar visceral fat burning qualities?

I think so. Specially if combined with oxandrolone plus TRT

 

I think so. Specially if combined with oxandrolone plus TRT

Oxandrolone promotes fat loss? What protocol would you recommend?

 

One of the studies I looked at used 20mg/d for 12 weeks.

 

I have been using Ipamorelin at 1mg/day, dosed at 500mcgx2, in the AM and before bed. This has the benefits of GH without the side effects. I have noticed better sleep, fuller muscles, strength, recovery etc.

The price is a little high at 1mg/day, but worth it.

I have used GH in the past, and for me way too much water retention, RHR and BP increase is a no go anymore.

 

I have been using Ipamorelin at 1mg/day, dosed at 500mcgx2, in the AM and before bed. This has the benefits of GH without the side effects. I have noticed better sleep, fuller muscles, strength, recovery etc.

The price is a little high at 1mg/day, but worth it.

I have used GH in the past, and for me way too much water retention, RHR and BP increase is a no go anymore.

U using ipa by itself? No GHRH with it?

 

U using ipa by itself? No GHRH with it?

Yes, I started to try it solo on a recommendation. It definitely lives up to what it is supposed to do, GH without the major side effects.

I have noticed only some swelling of the hands upon waking, and some daytime lethargy. I have not used any GHRH with it and I probably will not moving forward, apparently when you add in the GHRH there is an increase in side effects.

 

Yes, I started to try it solo on a recommendation. It definitely lives up to what it is supposed to do, GH without the major side effects.

I have noticed only some swelling of the hands upon waking, and some daytime lethargy. I have not used any GHRH with it and I probably will not moving forward, apparently when you add in the GHRH there is an increase in side effects.

Interesting about the possible increase in sides when using a GHRH with it. I’ve only used it in conjunction with cjc. Maybe I’ll give it a go by itself. Thanks for the anecdote and reply