Instant Blood Pressure Spike on Starting TRT

[ClashCityRocker]

Things aren't off to a good start, I'm afraid.

When I was examined by the endocrinologist last month, his office measured my blood pressure at 130/80. I'm typically about 128/78.

He started me on a relatively modest dose (0.4 mL/80 mg of Cypionate) once a week. I have primary hypogonadism, so my TT starting out was 465, with a FT of 6.8.

After my first dose, I felt a little revved up and had trouble sleeping. I decided for the next week I would split the dose (0.22 mL once every four days).

Well, I took the first dose of 0.22 mL and felt even more revved up. Today (3 days later) my BP is 141/93.

Nothing else has changed. No special stressors. Zero alcohol since starting TRT (before then, maybe 2 drinks a week). 5'9", 145 lbs. Lift 4 times a week; walk or hike on the other days.

The only other things I'm taking are 5mg of Creatine; vitamins C, D, & K; magnesium and zinc; and fish oil.

I'm obviously going to call the doctor before I take another dose, but does anybody have any perspectives or input?

 

[FunkOdyssey]

I'm obviously going to call the doctor before I take another dose, but does anybody have any perspectives or input?

It's pretty normal to see a transient increase in water retention and a transient increase in BP when you first start, before you adapt. Your baseline BP was already elevated, which gives you less headroom for these temporary effects. The "revved up" feeling is also temporary and will go away as you adapt.

You don't have to take your prescribed dose, if you're having trouble handling it at first. Feel free to take less if you need to. You can always increase later.

Caffeine makes everything that is bothering you worse, from the BP to the stimulation. Consider dropping it.

I had all the same problems you have at like 70 mg a week in the beginning, and I have since gone as high as 175 mg with no problem. This TRT thing is initially a big shock to your system but you will adjust to it given time.