Injection site level differences

GeauxBears

Active Member
I have historically injected sub-q via the fat above my hips, but recently have been bruising a lot and bleeding there, so I began to inject sub-q in my quads.

I didn't connect the dots at the time, but around the same time began to feel like I had crashed my E2 as I could not get an erection despite PDE5s + doxazosin. Finally got labs back today and holy crap. I have not changed my dosage at all. Has anyone else seen this? I may need to talk to Dr. Saya about a dose change because this is so drastic.

Current Protocol
TRT - 12mg daily
HCG - 500ius twice a week
Cabergoline - 0.125 twice a week
Anastrozole - 0.1 daily
Cialis - 5mg daily
Doxazosin - 1mg AM, 1mg PM
Armour - 60mg daily

Labs when injecting above hips
Total T - 752 ng/dl (300-1080)
Free T - 254.1 pg/ml (47.0-244.0)
SHBG - 11.6 nmol/l (16.5-55.9)
E2, Ultrasens - 14.5 pg/mL (10.0-42.0)

Labs when injecting in quads
Total T - 1237 ng/dl (300-1080)
Free T - 430.7 pg/ml (47.0-244.0)
SHBG - 13.2 nmol/l (16.5-55.9)
E2, Ultrasens - 23.6 pg.mL (10.0-42)

Any thoughts?
 
I don't know if this has any bearing on your situation: When injecting frequently with small doses it's at least possible for injection site leakage to cause significant variations in dosing compared to what's intended. I find that after an area has received multiple injections it can have minor swelling that seems to make leakage more likely. Site rotation may be helpful, and I also use a bright light to inspect each injection site a minute or two after the injection to see how much, if any, was lost.
 
I have historically injected sub-q via the fat above my hips, but recently have been bruising a lot and bleeding there, so I began to inject sub-q in my quads.

I didn't connect the dots at the time, but around the same time began to feel like I had crashed my E2 as I could not get an erection despite PDE5s + doxazosin. Finally got labs back today and holy crap. I have not changed my dosage at all. Has anyone else seen this? I may need to talk to Dr. Saya about a dose change because this is so drastic.

Current Protocol
TRT - 12mg daily
HCG - 500ius twice a week
Cabergoline - 0.125 twice a week
Anastrozole - 0.1 daily
Cialis - 5mg daily
Doxazosin - 1mg AM, 1mg PM
Armour - 60mg daily

Labs when injecting above hips
Total T - 752 ng/dl (300-1080)
Free T - 254.1 pg/ml (47.0-244.0)
SHBG - 11.6 nmol/l (16.5-55.9)
E2, Ultrasens - 14.5 pg/mL (10.0-42.0)

Labs when injecting in quads
Total T - 1237 ng/dl (300-1080)
Free T - 430.7 pg/ml (47.0-244.0)
SHBG - 13.2 nmol/l (16.5-55.9)
E2, Ultrasens - 23.6 pg.mL (10.0-42)

Any thoughts?
I did subq my first year. I’d get limos and bleeding. For the last two years I’ve alternated delts EOD. So much better. And I’ve moved from 27g 0.5 inch needles to 28g. If I warmed the test vial in warm water I could go to 29g like some do.

give it a try. I think you will like it better.
 
I did subq my first year. I’d get limos and bleeding. For the last two years I’ve alternated delts EOD. So much better. And I’ve moved from 27g 0.5 inch needles to 28g. If I warmed the test vial in warm water I could go to 29g like some do.

give it a try. I think you will like it better.
Edit lumps and bleeding
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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