Injecting once or twice a week is really dependent upon a few things:
1. If you just don't like injecting yourself than once a week will be better then twice a week.
2. If you have mid to high levels of SHBG once a week will help to lower SHBG levels freeing up more Free Testosterone which is a very good thing.
3. If you have low SHBG and higher E2 levels, twice a week is a much better protocol as it allows for a bit higher SHBG and doesn't provide for higher peaks and lower lows of Testosterone levels - think more stable levels week over week - and this is much more healthier for many men. I stopped using an AI on twice weekly injections!
There you have it.
What injection meds do you use and what dosages? Curious.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038