High SHBG - any way to lower?

[CanadaJim]

I recently was able to view lab results from 2018 to present day. Every time I have had lab work done (hormone panel) my SHBG is always higher than it should be. The higher than normal value presented even before I tried self prescribed TRT.
2018 (prior to testosterone) - Testosterone 26.9 nmol/l (Normal range 9.5 to 30)
- SHBG 57.4nmol/l (Normal range 11.0 - 50)
- Bioavail test 10.3nmol/l (Normal 4.8 to 14nmol/l)

2020 (after starting than stopping trt - 3-4 months 100mg weekly test cyp) - Testosterone 19.3
- SHBG 51.8
- Bioavail test 7.5
- Prolactin 6.8 ng/ml (3.5 - 19.4)
- Estradiol 112 pmol/l (<162) low

Subsequent blood work has also shown higher than normal SHBG with testosterone levels falling in the normal ranges. I haven't taken any testosterone since 2020.

Just wondering what could be contributing to lower SHBG and if this level could contribute to low libido and an overall feeling like my test is lower than it should be. Would starting trt at a higher dose address some issues or cause more?

Thanks

 

[CanadaJim]

I recently was able to view lab results from 2018 to present day. Every time I have had lab work done (hormone panel) my SHBG is always higher than it should be. The higher than normal value presented even before I tried self prescribed TRT.
2018 (prior to testosterone) - Testosterone 26.9 nmol/l (Normal range 9.5 to 30)
- SHBG 57.4nmol/l (Normal range 11.0 - 50)
- Bioavail test 10.3nmol/l (Normal 4.8 to 14nmol/l)

2020 (after starting than stopping trt - 3-4 months 100mg weekly test cyp) - Testosterone 19.3
- SHBG 51.8
- Bioavail test 7.5
- Prolactin 6.8 ng/ml (3.5 - 19.4)
- Estradiol 112 pmol/l (<162) low

Subsequent blood work has also shown higher than normal SHBG with testosterone levels falling in the normal ranges. I haven't taken any testosterone since 2020.

Just wondering what could be contributing to lower SHBG and if this level could contribute to low libido and an overall feeling like my test is lower than it should be. Would starting trt at a higher dose address some issues or cause more?

Thanks

Sorry - Correction - *What could be contributing to **higher SHBG levels...

 

[Systemlord]

Estradiol 112 pmol/l (<162) low

The estrogen isn't low, top of the range is 162 pmol/L or 30 pg/mL, therefore not low.

What could be contributing to **higher SHBG levels...

Genes, diet, liver problems and starvation which would improve insulin sensitivity and increase SHBG.

Just wondering what could be contributing to lower SHBG and if this level could contribute to low libido

As long as FT is optimal, that's all that matters.