Hematacrit lab accuracy and fluctuation throughout the day

So I had a CBC on Tuesday and didn’t think I was dehydrated, but my veins didn’t really show up very well so maybe I was and my hematocrit was 49.1. I decided to retest on Thursday and make sure I was hydrated and it came back at 44. My question is does anybody know how accurate the quest lab test is? I’ve always been told that hematocrit is usually accurate within 2 points depending on hydration but a five point swing seems like a lot. I suppose it’s possible that I was moderately dehydrated on the first test and slightly over hydrated on the second so the reality is somewhere in between.

I’ve just always looked at my hematocrit number as an absolute number and now I’m starting to realize that maybe if the lab is accurate that it really fluctuates that much based on hydration and I want to keep it lower than I would’ve otherwise to account for possible dehydration issues.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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