HCG and Water rentention

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Weasel

Member
I have used diuretics like hydrochlorothiazide when it gets bad with good results. But no more than once per week when it gets bad. I have to say that carbs (especially if I drink alcohol) and when I skip my 30 min of cardio at least 3 times per week, make it worse.

Just a warning to people about diuretics like hydrochlorothiazide, They can be very dangerous if not used properly! Be careful if venturing down this road.
 
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xqfq

Active Member
Yes, HCG can cause water retention and bloating in some men. It is not all estradiol related. I have been looking for data on its effect on aldosterone but have found nothing yet.

Several members have complained about this issue.

Water Retention from HCG
In some cases, it seems that water retention tends to normalize after a few weeks.

Water Retention Caused by Anabolics and Testosterone

I've been digging into this as well. Another factor may be that HCG, as an LH analog, could increase the production of the hormone Androstenediol:


There is not a lot of research on androstenediol, but it appears to have a strong affinity for the estrogen receptors. It isn't estradiol, but it could have similar effects. Per Wikipedia:

Androstenediol possesses potent estrogenic activity, similarly to DHEA and 3β-androstanediol.[2] It has approximately 6% and 17% of the affinity of estradiol at the ERα and ERβ, respectively.[3] Although androstenediol has far lower affinity for the ERs compared to the major estrogen estradiol, it circulates at approximately 100-fold higher concentrations, and so is thought may play a significant role as an estrogen in the body.[4]
Androstenediol - Wikipedia

I am not sure of the role this plays, but I expect that it's possible HCG could increase this hormone.

But on the flip side, HCG also may increase production of progesterone which can have diuretic effects. Women who experience bloating and water retention during their monthly cycle have this symptom when progesterone is lowest:



Note that estradiol doesn't dramatically decrease, but instead progesterone increases. See this study for some overview. See this study for some overview.
 

Nelson Vergel

Founder, ExcelMale.com
Just a warning to people about diuretics like hydrochlorothiazide, They can be very dangerous if not used properly! Be careful if venturing down this road.

They are the number one drug class used for high blood pressure. Potasium sparing ones are not dangerous.
 
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