Low shbg guy here, my E2 was high (33 through )doing 95mg a week (e3d pinning). Now I've been doing eod injections for the past two weeks but totsl T injected is still 95mg. Is that okay? Or do I need to make adjustment in dose too
You were on a protocol calling for injections every 3.5 days and posted an estradiol level you weren't happy with. Dividing the dose into smaller increments and injecting more frequently is designed to minimize the peaks of testosterone - in doing so it is expected that estradiol will not peak in testosterone's wake. At this point, and for at least four, if not six, weeks do nothing else as your serum levels adjust. Don't lower the dose, don't do, as I noted, anything else to your protocol. Test when time has passed.
All the best.
Thanks, I've noticed Everytime i make an adjustment, i get some bad anxiety and negative thoughts for 3- 4 weeks
But they resolve?
Yes, when I'd say it's worse when I increase my dose than decrease it. The adjustment causes more anxiety than actually higher e2
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038