madman
Super Moderator
Exercise & Nutritional Interventions: The Only Proven Strategies to Extend Human Healthspan | Dr. Mark Tarnopolsky | BlueOakNx Symposium
Dr. Mark Tarnopolsky delivers a clinically-grounded presentation drawing from 35 years treating mitochondrial disease patients, revealing critical insights about GLP-1 agonists, sarcopenia, and evidence-based strategies for healthy aging.
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Core Principles:
- Evolution is smarter than human intelligence—multi-ingredient supplements outperform single molecules
- Humans evolved as endurance runners; we eat complex foods, not isolated drugs
- USA has the longest healthspan-lifespan gap of any country studied
- Disability threshold: knee strength under 30 Nm = 50% need cane; under 10 Nm = 50% wheelchair use
Supplements/Drugs to improve health span/longevity?
Major Factors Related to Morbidity and Mortality