EW's TRT Journey

Talk to your doctor but would only use T3. I have also heard where Zinc really helps conversion of T4 to T3 and blocked RT3. Dr Westin Childs speaks of it.
 
You mentioned a few times that you are agro and got in a fight with your wife.... my bet is that was the HCG and the related estrogen spike. The AI won't help with this because the conversion is happening in the testes, not aromatising elsewhere.
 
You're fatigue and 'blah' could also be from the AI. I am not on the anti-AI bandwagon, but unfortunately I can't even handle a .125 dose.... the first 24 hours is great (calm, focused, great libido), but after 24 hours I get horrible brain fog and fatigue, and wicked constipation lol.

It's hard to tell what is causing what; you have so many variables. I love Defy and use them; they are very professional. But I think, from my humble experience, that they introduce too many variables (i.e. multiple medications) right off the bat, and at high doses.
 
You mentioned a few times that you are agro and got in a fight with your wife.... my bet is that was the HCG and the related estrogen spike. The AI won't help with this because the conversion is happening in the testes, not aromatising elsewhere.

Yeah, I was getting really bitchy/sensitive and dialed my HCG WAY back and have felt pretty good ever since.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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