Endogenous sex hormone levels have no effect on mortality

Jinzang

Member
"[Testosterone] exhibits neutral association with all-cause or CVD mortality or incident CVD events in a cohort of predominantly middle-aged men,” the researchers wrote. “Further studies are required to clarify the age-dependent effects of [testosterone] and to examine the relationship between [testosterone] and disease over time.”

Read the executive summary of the study
 
Thank you. Yes, that study supports previous data:

Testosterone, DHT and Estradiol and Mortality in Older Men

www.excelmale.com/showthread.php?8120...DHT...Mortality-in...

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2408 Testosterone Is Associated With Reduced All-Cause Mortality and Higher Dihydrotestosterone With Reduced Ischemic Heart Disease ...

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Testosterone , DHT and E2 do not influence mortality in middle-aged ...

www.excelmale.com/showthread.php?6946...DHT...mortality...

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Neutral associations of testosterone, dihydrotestosterone and estradiol with fatal and non-fatal cardiovascular events, and mortality in men ...

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Thread: Decline in Testosterone, Estradiol and DHT is Associated ...

www.excelmale.com/showthread.php?6386...in...Mortality...

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Temporal Changes in Androgens and Estrogens are associated with All-Cause and Cause-SpecificMortality in Older Men - See more at: ...

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Low testosterone is a better predictor of mortality than sarcopenia in ...

www.excelmale.com/showthread.php?5401...is...mortality...

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Low testosterone is a better predictor of mortality than sarcopenia in men with advanced liver disease Journal of Gastroenterology and ...
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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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