Do statins affect erections in men?

statins and ed.gif


Question:

Do statins affect erections in men?

Answer:

The science on statins and sexual function is inconclusive, but it does appear that taking a statin may sometimes affect a person's sex life.


Researchers looked at statin use and sexual function in 1,000 men and women, half of whom were given a statin and half of whom took a placebo. Over all, men on statins were about twice as likely as those taking placebos to report that their ability to achieve orgasm had become “somewhat worse” or “much worse.”

Dr. Beatrice Golomb, a professor at the University of California, San Diego, medical school, who helped conduct that study, says doctors don't always take patients seriously when they talk about side effects, sexual or otherwise. In other research, Dr. Golomb found that when patients complained about the most commonly recognized side effects of statins, their doctors denied the possibility of a connection more than half the time.

Medical problems that lead to a statin prescription might also be to blame for changes in sexual function, said Dr. Natan Bar-Chama, director of male reproductive medicine at Mount Sinai Hospital in New York. Statins are commonly prescribed for people with ailments such as diabetes or heart disease, which can cause erectile dysfunction. If the underlying disease improves when someone takes statins, then erectile function is likely to improve as well, he said.

Ask Well: Statins and Your Sex Life


Do Statins Affect Erections in Men?​

The relationship between statin medications and sexual function remains a subject of scientific debate, with research suggesting that these cholesterol-lowering drugs may sometimes impact a person's sex life, though the evidence is far from conclusive.

What the Research Shows​

A significant study examined statin use and sexual function in 1,000 participants, divided equally between those receiving statins and those taking placebos. The findings revealed that men taking statins were approximately twice as likely as those on placebo to report that their ability to achieve orgasm had deteriorated, describing it as "somewhat worse" or "much worse."

Dr. Beatrice Golomb, a professor at the University of California, San Diego medical school who participated in this research, notes an important concern: physicians don't always take patients seriously when they discuss side effects, whether sexual or otherwise. Her additional research uncovered that when patients reported even the most commonly recognized side effects of statins, their doctors denied any possible connection more than half the time.

The Complicating Factor​

The picture becomes more complex when considering the underlying health conditions that typically lead to statin prescriptions in the first place. Dr. Natan Bar-Chama, director of male reproductive medicine at Mount Sinai Hospital in New York, points out that statins are commonly prescribed for conditions such as diabetes and heart disease—both of which are known independent causes of erectile dysfunction.

This creates a challenging situation when trying to identify the true cause of sexual dysfunction. If the underlying cardiovascular disease or metabolic condition improves with statin therapy, erectile function may actually improve as well, according to Dr. Bar-Chama. This suggests that in some cases, the benefits of treating the underlying condition with statins may outweigh any potential negative effects on sexual function.

The Bottom Line​

While research indicates a potential link between statin use and changes in sexual function, particularly regarding orgasm achievement, the science remains inconclusive. The interplay between the medications, the underlying diseases they treat, and sexual function makes it difficult to draw definitive conclusions. Men experiencing sexual dysfunction while taking statins should discuss their concerns with their healthcare provider, who can help determine whether the medication or the underlying condition is the more likely culprit.
 
Last edited:
Nelson Vergel

Nelson Vergel

test, I remember that study it was very controversial. I use health diagnostic laboratories and they do recommend me using instant release niacin. My main concern is my "small" ldl particles and I do everything possible to keep them under control:)
 
Just found this article on statins. I saw a news report this week advocating the use by more people to use them. Very disappointing indeed, but not surprising that big media would be in bed with big pharma. I personally had a very bad reaction to generic Zocor which could have cause permanent muscle damage.

The Grave Dangers of Statin Drugs—and the Surprising Benefits of Cholesterol – Alliance for Natural Health USA – Protecting Natural Health

--------------------------------------------------------------------------------------

Statins interfere with the production of coenzyme Q10, which supports the body's immune and nervous systems, boosts heart and other muscle health, maintains normal blood pressure, and much more.
Statins weaken the immune system, make it difficult to fight off bacterial infections, and increase the production of cytokines, which trigger and sustain inflammation.
They make some patients unable to concentrate or remember words, and are linked to muscle and neurological problems, including Lou Gehrig's Disease.
Statins inhibit the beneficial effects of omega-3 fatty acids by promoting the metabolism of omega-6 fatty acids, which increases insulin resistance and the risk of developing diabetes.

There is evidence that statin use blocks the benefits of exercise. Exercise increases the activity and numbers of mitochondria, cells' “power plants” that process sugars and fat. The study found that with statin use, mitochondrial activity actually decreases with exercise.
Statins work by reducing the body's ability to produce cholesterol, which is essential to brain health—the brain is 2% of the body's weight, but contains 25% of the entire body's cholesterol.
Statin users have a higher incidence of nerve degeneration and pain, memory loss, confusion, depression, and a higher risk of ALS and Parkinson's, according to Dr. David Williams in his July 2014 Alternatives newsletter. Statins also decrease carotenoid levels. Carotenoids, which are found in fresh fruits and vegetables and act as antioxidants, have a number of benefits, including protecting against cell damage, aging, and chronic diseases.
Statin drugs may also be driving Americans to overeat: a twelve-year study published in JAMA Internal Medicine found that statin users increased their calorie intake by 9%, and fat consumption by 14.4%, over the study period, whereas those who didn't take statins didn't significantly change in either measure.
An animal study linked statin use to muscle damage. Animals that exercised on statins had 226% more muscle damage than those not given statins.
They affect the quality of sleep.
Statins increase the risk of prostate and breast cancer.
Statins are known to cause liver damage by increasing the liver's production of digestive enzymes.
Statins also speed aging and lower sex drive.
Statins have been linked to aggressive and violent behavior in women.
 
I'd treat that link with a bit of skepticism. This is obviously a supplement industry shill group, everything about conventional medicine is bad, bad, bad; and they promote supplements. Not going to trust these people. That is not to say I trust statins or conventional medicine all that much, but too many people play strawman arguments with this debate, conventional is bad and doctors are in the pay of the big pharms, so by definition supplements must be good.

BS.

Fact of the matter, everything I read is that statins have a better safety track record than I expected, but I still would do everything I can to stay off them - or any medicine / supplement.

There is nothing out there - pharms or supplements that are 100% safe. And the majority of supplements have minimal medical or scientific research or clinicals to prove their efficacy or their safety.
 
I have a neighbor that was put on a statin and I watched him go down hill for over a month. He looked like he aged 10 years. His wife came talked to me saying how sick he was and how he couldn't get enough to drink. I told her it sounds like diabetes and I will be over with a meter to check. I checked his glucose and the meter said error. The meter manual says it can't read anything over 600. He goes to doctor and tells them no more statins and they put him on metformin and has been in normal range from then on. There was no diabetes problem before that statin.
 
Nelson,

I been on statins for more than 15 year and so far no problems. I have genetically high cholesterol and if not medicated it shuts up to above 300. There is very little I can do to lower it really because my liver naturally produces all that cholesterol and dieting is just a help of 10-15%. I can drink just water for a 3 week and still I would have high cholesterol. I believe there must be a reason for this.
More and more I am becoming convinced that the statins drugs are just making things worse. According to studies done: 50% of people that drop stone dead due to strokes and heart attacks had normal cholesterol values. So what conclusion can we draw from these facts?
Anyway If I understand your writing could be that progesterone might be a supplement to consider or? I wouldn´t like it but!!
“LH responsiveness of Leydig cells was only maintained when progesterone was used to bypass the site of action.” ?
Hi,
Did you notice any changes after reducing your cholesterol and triglycerides levels like improve in erections?
 
When that study came out in 2014, I stop using niacin. There was never any more studies done, say that niacin and was bad. Since there wasn't much support to the study. I did start using niacin a short time later again.
I remembered when i asked my dad to take niacin along with lipitor and he got severe side effects like hot flash and sweating.
We should take either one of them.
When i took lipitor for a month, i got improvement in erections like really good. I also did blood work and my cholesterol was low and it got back high right after quitting. Dint even take 2 weeks.
 
I remembered when i asked my dad to take niacin along with lipitor and he got severe side effects like hot flash and sweating.
We should take either one of them.
When i took lipitor for a month, i got improvement in erections like really good. I also did blood work and my cholesterol was low and it got back high right after quitting. Dint even take 2 weeks.
Yes, that's very common. That's why people use endur-acin or slow-niacin. Pure niacin you get a niacin flush and stomach irritation.
Endur-Acin Side Effects by Likelihood and Severity
COMMON side effects


If experienced, these tend to have a Less Severe expression


  • Cough
  • Diarrhea
  • Indigestion
  • Itching
  • Nausea
  • Temporary Redness Of Face And Neck
  • Vomiting
 

Association between statin use and erectile dysfunction: Results from the National Health and Nutrition Examination Survey​

  • Sheng Chen, Jianqiang Zhang
    Published in Medicine 31 October 2025
TLDR

A positive correlation between statin use and ED prevalence in a representative sample of the American male population is identified, highlighting the necessity for a balanced approach in prescribing statin, particularly among populations at risk of ED.

Abstract
This study aimed to examine the association between statin use and the prevalence of erectile dysfunction (ED) among a diverse cohort of American men aged 20 years and older, utilizing data from the National Health and Nutrition Examination Survey for the years 2001 to 2004. The analysis employed Logistic regression was used to assess the relationship between self-reported statin use and ED, adjusting for potential confounders, including age, ethnicity, educational level, smoking habits, diabetes mellitus, body mass index, alcohol consumption, hypertension, and hyperlipidemia. The initial participant pool consisted of 21,161 individuals, which was narrowed down to 3767 eligible subjects after applying the exclusion criteria. ED was evaluated based on the participants’ self-assessment of their ability to obtain and maintain an erection sufficient for satisfactory sexual performance. The study identified a statistically significant association between statin use and an increased prevalence of ED, with an odds ratio of 4.66 (95% confidence interval [CI]: 3.74–5.81) in the crude model. After adjustments for demographic, lifestyle, and health factors, the association remained significant, albeit reduced (odds ratio: 1.77, 95% CI: 1.34–2.35). Subgroup analysis highlighted variable correlation levels among different demographic and health-related groups, with age and body mass index identified as potential modifiers of the relationship between statin use and ED. Our findings indicate a positive correlation between statin use and ED prevalence in a representative sample of the American male population. This association, persistent across various subgroups and after adjusting for multiple confounding factors, underscores the need for further research to elucidate the underlying biological mechanisms and inform clinical decision making. The implications of this study suggest the necessity for a balanced approach in prescribing statin, particularly among populations at risk of ED, highlighting the importance of considering potential side effects in managing cardiovascular risk factors.
 

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Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

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