Some guys have said they feel better with daily dosing. I'm doing daily now and I can't say I notice much difference from when I was doing EOD.
Yes, during an unusual period of undetectable estradiol that occurred when I paused use of hCG. Estradiol seemed to be rebounding to normal—high—levels even before I resumed hCG. I have gone for long periods without an AI and estradiol in the 50s pg/mL. The symptom of excess emotionalism was kind of interesting, but I eventually got tired of it and started micro-dosing anastrozole. This puts estradiol in the 30s, still higher than the 0.3% of testosterone mentioned by Nelson.That's quite a turn of events, if I am not mistaken didn't you once post you were taking estrogen to increase your E2?
Yes, during an unusual period of undetectable estradiol that occurred when I paused use of hCG. Estradiol seemed to be rebounding to normal—high—levels even before I resumed hCG. I have gone for long periods without an AI and estradiol in the 50s pg/mL. The symptom of excess emotionalism was kind of interesting, but I eventually got tired of it and started micro-dosing anastrozole. This puts estradiol in the 30s, still higher than the 0.3% of testosterone mentioned by Nelson.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038