Cycle HCG?

Shad0w

Member
Hey guys, I was wondering if HCG needs to be cycled? I just started a week ago with 500iu’s twice a week. If it does need to be cycled, for how long off and on? And as far as dosage, is 250iu eod better than 500 e3.5 days? My main concern is desensitizing receptors and possibly permanently shutting down the testicles. I’m secondary hypogonadism and know that they work properly. The reason I started trt in the first place was because I took a sketchy workout supplement a few years ago (which was taken off the market) and never seemed to start my own production back up. I’ve only been on trt for about 7 months and am really wondering if I could come off test completely and get my own production jumpstarted with the hcg? Any thoughts or advice is appreciated.
 
HCG is suppressive and only stimulates the half of the testicles, you want to jumpstart your HPTA use clomid. Personally I believe when the damage is done there's no going back and if you are nearing 30 testosterone is supposed to be on the decline by then anyhow.

As far as desensitizing LH receptors, that tends to happen at very high dosages.
 
I just turned 25 two days ago. If I did try to come off the testosterone would I run just hcg and then transition to clomid? Or run the two together?
 
There is no need to cycle HCG. Cycling drugs (such as high volume AAS) is usually implemented because at such doses it has a detrimental effect. In most cases those who can get on with HCG at the small doses taken for TRT this is not the case.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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