IN that same chain were we speculate or think we know HCG can start that downstream production, in most of us on the forum I think experience some sort of dysfunction in that area, maybe enzyme related. But obvious not working as one wouldn't need to use Preg or DHEA, et al.., if HCG would spur that conversion.We know the chain is HCG-->pregnenolone--->progesterone---->17-hydroxyprogesterone, which converts to cortisol. Is this why it is common to have issues with HCG? Seems people on the forum are moving away from HCG.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038