Can Testosterone Actually Cure Prostate Cancer?

madman

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Summary

Dr. Samuel Denmead discusses the use of testosterone therapy to treat aggressive metastatic prostate cancer. By administering high doses of testosterone in a bipolar fashion, where levels fluctuate between super physiological and low, it has shown promising results in shrinking tumors and improving quality of life for patients.



Highlights

  • Testosterone therapy challenges the long-standing belief that androgens cause prostate cancer, instead showing potential benefits in treating the disease.
  • The bipolar testosterone therapy involves giving patients high doses of testosterone followed by low doses, which can sensitize the cancer cells and lead to tumor shrinkage.
  • The therapy has been found to improve muscle mass, decrease fat, and increase energy levels in patients.
  • More research is needed to optimize the therapy, understand the effects on different stages of prostate cancer, and explore the role of diet and microbiome in the treatment.
  • Clinicians are encouraged to keep an open mind and consider testosterone therapy as a potential treatment option, while also addressing heart health and other factors that may impact the patient’s overall wellbeing.
 


 
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Screenshot (27532).webp
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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