Can DHT actually reduce the need for AI?

Weasel

Member
I've read this a few times around the web that increasing DHT can lower or remove the need for an AI but its always bro science best I can tell. Does DHT actually reduce e2 or just hide its effects?

Can anyone confirm this can happen or deny it?
 
I too read this. I was using a cream on the scrotum daily jsut for DHT purposes as I've tested below 50% on the lab ranges several times...cream works well but has to be used everyday, lab tests showed my up at the top or sometimes just above the lab max. Concurrently I was running very high E...50/60/70, as high as 88 at one time. While I was trying to figure out why my E was so high I systematically eliminated several things and that cream was eventually one of them. I eventually had to get on Anastrozole, but I do think that the DHT was helping blunt some of my E symptoms. For instance I was warm in bed but not hot or sweaty, and I was very easily angered; PMSish. For my E being that high, I did think that I would have much more pronounced symptoms. I never really felt like my E was that high. So maybe it helped blunt the symptoms, maybe not, I can't say for sure.
 
I too read this. I was using a cream on the scrotum daily jsut for DHT purposes as I've tested below 50% on the lab ranges several times...cream works well but has to be used everyday, lab tests showed my up at the top or sometimes just above the lab max. Concurrently I was running very high E...50/60/70, as high as 88 at one time. While I was trying to figure out why my E was so high I systematically eliminated several things and that cream was eventually one of them. I eventually had to get on Anastrozole, but I do think that the DHT was helping blunt some of my E symptoms. For instance I was warm in bed but not hot or sweaty, and I was very easily angered; PMSish. For my E being that high, I did think that I would have much more pronounced symptoms. I never really felt like my E was that high. So maybe it helped blunt the symptoms, maybe not, I can't say for sure.


Interesting VC,

I brought this topic up for the same reason. Cream should be here this Thursday. DHT is always %50 or less of range. I'm currently using Anstrozole but having a very hard time finding my sweet spot with it.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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