Brain health with trt, missed sleep

I (m, 37) take 20mg testosterone proprionate IM and 150 IU Hcg IM.

I noticed while travelling, that when I missed a night of sleep then the next day I didnt sleep much more. And I just can go on and still look the same and not much tired or something.

I read about studies that showed that users of steroids had markers of brain damage that were comparable to cocaine etc users. Dopamine system and so on.

Does the brain clean and repair itself even while awake or will this accumulate damage at this dosages with sleep deprivation?

In my experience it seems to hinder memory consolidation at least. Wondering if this will damage hippocampus or other areas of the brain. It seems quite deceptive as the body seems looking fresh and the mind has energy still.

Are there any crucial supplements? I take NAC, NMR, Vit D, Vit C, B6, B12, Kreatine, Omega3, 1mg of melatonin. Maybe vitamin E missing?

I heard good stories about methylene blue, microdosing psychedelics for increasing bdnf and high doses of melatonin.

Also lots of proteins seem to help with sleep deprivation.

Any other harm reduction advices?
 
Last edited:
I (m, 37) take 20mg testosterone proprionate IM and 150 IU Hcg IM.

I noticed while travelling, that when I missed a night of sleep then the next day I didnt sleep much more. And I just can go on and still look the same and not much tired or something.

I read about studies that showed that users of steroids had markers of brain damage that were comparable to cocaine etc users. Dopamine system and so on.

Does the brain clean and repair itself even while awake or will this accumulate damage at this dosages with sleep deprivation?

In my experience it seems to hinder memory consolidation at least. Wondering if this will damage hippocampus or other areas of the brain. It seems quite deceptive as the body seems looking fresh and the mind has energy still.

Are there any crucial supplements? I take NAC, NMR, Vit D, Vit C, B6, B12, Kreatine, Omega3, 1mg of melatonin. Maybe vitamin E missing?

I heard good stories about methylene blue, microdosing psychedelics for increasing bdnf and high doses of melatonin.

Also lots of proteins seem to help with sleep deprivation.

Any other harm reduction advices?
My advice. Don't use Anabolic steroids.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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