I'm a fan of B12, especially going with methylcobalamin injections. IMO, you don't have to go overboard .. 250mcg -to-500mcg a week is good. Run labs in 4 to 6 weeks, see where everything is at. For me, it doesn't have to be administered every week. I can do every other week and be just fine. Keeping an eye on iron, ferritin, HCT (as you mentioned), along with cortisol & thyroid are equally important to ensure a good program.