Androgel Failed and rose PSA

Rclouviere

New Member
i switch to injections, from androgel will this increase my psa like the androgel did? Im 67 and definitely need trt, but don’t want to jeopardize my prostrate. Please help.
 
Due to individual variation there's no fixed answer. In switching to injections you will likely produce less DHT, which could be helpful. But it's also easier to attain very high testosterone levels with injections, which could be counterproductive. Your best bet is to start injections with a low dose and only increase slowly as needed. A low dose is something like 14 mg of testosterone cypionate injected every other day. This is still delivering an average of 5 mg of testosterone per day, which is not much below the 6-7 mg that healthy young men can produce naturally. If you still have problems then there are alternatives, such as a testosterone nasal gel, e.g. Natesto, or injections of a cypionate/propionate blend, which also allows for a reduced dose of testosterone while still preventing hypogonadism. Using the latter method I have successfully used as little as 3.7 mg of testosterone daily without having any signs of low testosterone. In fact peak serum levels are still above average.
 
Your PSA levels can be affected by many different factors. While an elevated PSA level doesn’t necessarily indicate prostate cancer.
Not common but one could have prostate cancer and normal PSA.
Here the health insurance stopped paying for PSA tests because the test results proved unreliable for prostate cancer screening.

 
i switch to injections, from androgel will this increase my psa like the androgel did? Im 67 and definitely need trt, but don’t want to jeopardize my prostrate. Please help.
Usually injection affects your prostate less. That's one reason I never used androgel. I'll show you my protocol.

 
Usually injection affects your prostate less. That's one reason I never used androgel. I'll show you my protocol.

What was your psa?
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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