6 months on TRT review of blood work

brandonleeh

New Member
Hi Everyone,

This is my first post on here, just wanted to give an overview of my background and history with ED and no libido.
I'm 45 and have suffered on and off with ED for around 25 years, my low testosterone was flagged up back in my mid 20,s but as it was just within range bugger all was done about it.
After many years of trying this and that I settled on self administrating trt due to no NHS doctors being capable of helping.

Started in June 2025, daily subq injections of test cyp, started at 10mg with 250iu HCG EOD.
Had blood work done every 8 weeks and assessed symptoms.
I've gradually over several months worked up to 17mg per day, which was the first dose after 8 weeks that gave symptoms relief, morning erections started and things started to feel normalish.

Here's the blood work for this dose
Testosterone 34.9nmol
Oestrogen 284. Pmol
Prolactin 262
Free test 0.935
Shbg 21.1
Dhea 6.3

Due to oestrogen and testosterone being out of range I reduced to 15mg per day
And all the morning wood went away and I feel flat as hell.
Blood work now looks like this

Testosterone 28.5 nmol
Oestrogen. 236pmol
Prolactin 260
Shbg 20.9
Dhea 6.3
Iron 36ug/l
Haemocrit 0.501
Red blood cell count 5.61 (4.5-6.5)
Haemoglobin 36mmol

So the question is, do I stay at 15mg and work on reducing oestrogen and potentially start giving blood even though irons a bit low?
It's frustrating that 17mg per day felt great but would only exacerbate issues above

Sorry thats a lot to read
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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