6 month update and E2 question

[Rkhal]

Update
I have been on TRT for about 6 months so far and it has been great. My TSH since being on TRT has dropped from 3.7 to 1.69 which is great (I am not taking an idione supplement or anything). My only concern is my estrogen, my latest blood test came in at:
Total T: range: 264-916 - result: 1241
free T: 8.7-25.1 - result 20.7
estradiol sensitive- 8-35 result 47.9
my doctor does prescribe arimidex to patients but doesn’t think I need it. I don;t think I have a ton of high e2 symptoms but I def have a fair bit of water retention (can tell by my face and ring finger).
Any input on my E2 lvls? I feel really good since starting TRT by the way, no complaints really.
(by the way my protocol is 70mg test 2x per week and HCG 40 units 2x per week)

 

[Nashtide]

Update
I have been on TRT for about 6 months so far and it has been great. My TSH since being on TRT has dropped from 3.7 to 1.69 which is great (I am not taking an idione supplement or anything). My only concern is my estrogen, my latest blood test came in at:
Total T: range: 264-916 - result: 1241
free T: 8.7-25.1 - result 20.7
estradiol sensitive- 8-35 result 47.9
my doctor does prescribe arimidex to patients but doesn’t think I need it. I don;t think I have a ton of high e2 symptoms but I def have a fair bit of water retention (can tell by my face and ring finger).
Any input on my E2 lvls? I feel really good since starting TRT by the way, no complaints really.
(by the way my protocol is 70mg test 2x per week and HCG 40 units 2x per week)

I think if you feel great then the E2 is okay. I wouldn't want it to get too much higher. Your TT is pretty high. Were the labs pulled at trough? If so, you may run into HCT issues in the future. Lowering your T dose will lower your E2, but I hesitate to change anything since you're feeling so good. The hcg dose is a little strange. That's a very small amount.

 

[Rkhal]

What is HCT? Yep labs at trough before my injection. Typo it is 400 on hcg

 

[Systemlord]

You could easily adjust your dosage to bring E2 in range, AI do nothing good for you in the long term. An AI is a last resort in an attempt to control high E2 with a minimal dosage possible.

 

[Vince Carter]

You might consider a trial of 200mg DIM with 500mg Calcium D Glucarate for a month. Neither will lower or block E but could help your body process it out better and thus fewer symptoms.

 

[Rkhal]

You could easily adjust your dosage to bring E2 in range, AI do nothing good for you in the long term. An AI is a last resort in an attempt to control high E2 with a minimal dosage possible.

What type of dose adjustment do you think is in order to bring E2 into range? Try 65mg 2x per week and check bloodwork in 2 months?

 

[Nashtide]

What is HCT? Yep labs at trough before my injection. Typo it is 400 on hcg

Hematocrit. If it gets too high, you run the risk of blood clots and stroke.

 

[Nashtide]

What type of dose adjustment do you think is in order to bring E2 into range? Try 65mg 2x per week and check bloodwork in 2 months?

How old are you? Concerned with fertility? If not, you could lower your hcg dose.

 

[Systemlord]

What type of dose adjustment do you think is in order to bring E2 into range? Try 65mg 2x per week and check bloodwork in 2 months?

Honestly I don't think a 10mg reduction will be enough, 60mg twice weekly. HCG impacts E2 levels possibly even more.

Your next move in 2 months will depend on your HCT.

 

[Rkhal]

Hematocrit. If it gets too high, you run the risk of blood clots and stroke.

oh yeah, I donate every 2 months, I believe there are health benefits to this plus I'm helping people. My hematocrit has not been above 47

 

[Nashtide]

oh yeah, I donate every 2 months, I believe there are health benefits to this plus I'm helping people. My hematocrit has not been above 47

Awesome! So back to the original issue. This should be obvious, but the only legitimate way to decrease your E2
without an AI is to reduce your T or hcg dose. A good starting point is to decide where you want your E2. If you want to reduce your E2 by say 20% then reduce your T dose 20% and re check in 6 weeks.