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  1. W

    Very Low IGF-1 and IGF Binding Protein 3 levels. Advice?

    Hello. Long time lurker here but this is only my 2nd post. I'm 20 years old but for some reason, my IGF-1 and IGF BP-3 levels are extremely low. The Z-score is really bad, so I am literally 1.65 standard deviations below a healthy level for my age. I have had this tested multiple times by...
  2. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    Big n-1 results update. With all the gym bros telling me for the last 10 years that GH secretatgogue peptides are a scam and a waste of $$$$ - and that good ol' GH is superior and the only way to go - - - Let me preface this post by saying that these peptides do work. I repeat. THESE PEPTIDES...
  3. G

    Some labs out of range -- would you change anything?

    Hi All, My question is: Given my data below -- would you change anything? Me: 61yo, 5'10", 165lbs, TRT for nearly 2 years. I've titrated up over that time up to current .10mg test cyp SQ daily (last 6 months). Good body composition, good energy, good cognitive function, good libido/sexual...
  4. FunkOdyssey

    How much does TRT typically boost IGF-1 level?

    Here's my sad pre-TRT IGF-1 value: How much do you think this is going to go up on 105 mg test cyp weekly? I will follow up with test results but I'm curious what others have seen.
  5. J

    What causes low prolactin and IGF-1 when all else looks great?

    I received my new labs after 8 weeks on my new protocol. I don't take T. I take HCG 250IU x4wk and 50mg enclomiphene x 4wk. TT is 956 ng/dL r264-916, FT 17.3 pg/dL r6.6-18.1, E 38.4 pg/dL r7.6-42.6, but prolactin is 3.6 ng/dL r4.0-15.2, and IGF-1 65 ng/mL r64-240. I'm concerned about the...
  6. L

    MK-677 and my IGF-1 Levels

    Recently, I started working out and lifting more. I read about MK677 Ibutamoren, and wanted to try it to increase my HGH and IGF-1, so I ordered some from Supreme Labs USA. I hadn't tested my IGF-1 levels in a few years, and I wanted to know my baseline before taking it. Got tested on 4/18/22...
  7. RP McMurphy

    First Lab Post! “Should I stay or should I go?”...would appreciate some guidance. Thank you!

    I’m a 45 yo male, 150 lbs. Prior to starting any testosterone therapy my labs in January 2018 were in range (Total T 601 280-1100ng/dl, Free T 10.43 1.9-27ng/dl), but I wanted to see if increasing testosterone levels would help to improve fatigue. I always had a high sex drive, with decent...
  8. T

    Exogenous growth hormone and IGF-1

    Do any of you know.. if one takes exogenous GH, how soon IGF-1 levels drop to baseline after stopping? @Cataceous
  9. T

    IGF-1 and Growth hormone

    Has any one of you guys been on growth hormone and know your pre- and post IGF-1 labs? What source did you go through and did you notice a difference? I found out my IGF-1 is well on the lower end, consistently. But not enough for treatment. @Nelson Vergel @Cataceous
  10. Z

    High Testosterone and anxiety

    So I got some Of my labs back and the basics are my T was 1477 Free T-47 SHGB was 30 Hemocrit was 51 Hemoglobin was 17 IGF-1 was 180 PSA-0.6 this was done 24 hours after my last injection. I do 25mg everyday. But my question is, my anxiety has been a little on the higher side lately. I know...
  11. J

    IGF-1 and Free T Increase Prostate Cance Risk

    From an article on the study: Risk was estimated using multivariable-adjusted Cox regression in 199,698 male UK Biobank participants. 2-sample Mendelian randomization (MR) analysis of IGF-I and risk used genetic instruments identified from UK Biobank men and genetic outcome data from the...
  12. T

    Optimum IGF-1 Levels

    Can't seem to find a prior thread on the optimum IGF-1 levels. My pre-TRT IGF-1 levels were 233 ng/ml (with a range of 75-216 ng/ml). I am about to start enclomiphene (12.5mg/daily) and ibutamoren (12.5mg/daily). The ibutamoren was prescribed after complaining about some nagging gym injuries...
  13. C

    Any reason to use hgh as a under 30

    Hello Is there any reason to use growth hormone as under 30 years old? I would like to see what effect it have on my skin , sleep and wellness. Mainly my skin. I ve used pramipexole in a past for high prolactin and thats is known to increase hgh levels temporaly, i got awesome skin results from...
  14. D

    Nandrolone (Deca Durabolin): Effect on Lab Tests

    PARTICIPATION NEEDED! Of those EM members that have taken nandrolone or are currently taking nandrolone alongside their TRT, we are conducting a small ExcelMale study to help determine the effect that nandrolone has on Total Testosterone, E2, Prolactin, SHBG, free T, and DHT while taking TRT...
  15. A

    Reason for High IGF-1?

    I am posting my blood results. This is before i started TRT which is on feb 14th. Blood was drawn on feb 10. Wondering what is the reason for high IGF-1 or somatomedin? I have low testosterone, low rbc and high cholestrol. I also have high normal blood sugar. Can any experts tell what is going...
  16. F

    High IGF-1 Is this something to worry about?

    Igf-1 level says HIGH at 239 ng/ml (75-216) Im not even sure what this means or what it does.. but is it something to worry about?
  17. K

    How to lower IGF 1 ?

    Is there a proven way or supplement for lowering IGF1 ? Besides the internet BS regarding diet .
  18. G

    How Much Are You Paying for MK-677 - Ibutamoren?

    Anyone using MK-677? If so, how much is it costing you, and what’s your experience with it? Thanks.
  19. G

    Anyone use peptides?

    Interested in Tesamoreli and Ipamorelin. Does anyone use either of those? If so, how much is it costing you? Thanks.
  20. Gianluca

    high IGF-1a concern?

    Didn't quiet get the chance to talk to Doc about this result, Dr Saya if it happens you see the post I would appreciate your comment about it. IGF-1 come back at 333 on a scale of ng/mL 88 - 246, to mention I took the test after a meal containing high biological value protein, I guess my IGF-1...
  21. Nelson Vergel

    Higher IGF-1 and DHEA levels, longer telomere lengths

    Your life expectancy grows, the more anabolic – and fewer catabolic – hormones your body produces. Researchers at Harvard Medical School reached this conclusion after performing a molecular-epidemiological study on 925 men and women over the age of 54. The more anabolic hormones your body...
  22. A

    IGF-1 LR3 vs. Ipamorelin CJC1295

    Hello, New member here. Thank you Nelson for this great site. I have learned a lot of very helpful information in a short period of time, contacted members directly, and now have located a provider to analyze my labs. I have been researching this site and the web. Does anyone have...
  23. DragonBits

    IFG-1, IGF-1 signaling, good or bad?

    I am a little confused about IGF-1 issues. There is a thread suggestion that higher IGF-1 levels are good for your health, and drugs are sold to stimulate GF/IGF-1 production. On the other hand, Metformin is a drug that is often recommended for glucose control as well as its anti-aging...
  24. R

    Testosterone now 700+ and I still feel like crap, what's next?

    Briefing I'm a 33 year old male I started having libido swings In 2015 while my wife was pregnant but no erection issue. Weeks of my usual high libido then a week of low libido And about 9 months later I experienced Ed out of the blue so I went to my urologist and he put me on 25mg of clomid...
  25. DragonBits

    What blood tests have reference ranges that depend on age?

    We know some reference ranges on blood test are adjusted for age, but I don’t know which ones are and which aren’t. This is important because it tells us if we are over or under range, creates flags on blood tests, may concern patients or doctors. Recently Dr. X contributed the fact that...
  26. E

    IGF-1 came back very elevated. I'm panicking. How concerned should I be?

    Background I'm 36. On TRT for six years. 6'2", 215lbs. Have had my GP manage my TRT and have never gotten specialist care to get dialed in. I'm in the process of signing up with Defy Medical to have Dr. Saya manage my TRT. My GP has had me on 50,000 IU per week of Vitamin D2 after I came back...
  27. Nelson Vergel

    IGF-1 Roles and Benefits

    By David Skutt IGF-1, What is it? IGF-1 is a hormone produced in our body that is structurally very similar to insulin. It has an important role in growth during childhood and in adulthood, continues to have anabolic effects. IGF-1 is the main mediator of the effects of growth hormone, which...
  28. J

    Bloods All Over The Place - Suggestions?

    Brief history - found a tumor in my pituitary gland, and was prescribed HRT almost 12 months ago, namely HGH and TRT. I've also had several spinal surgeries and some nagging pains, so decided to try out a therapeutic Nandrolone Decanoate (Deca) dose recently. My protocol for the past 6 months...
  29. Nelson Vergel

    Men with high levels of anabolic hormones less likely to develop worsening frailty

    The researchers found that having higher baseline levels of vitamin D, insulin-like growth factor-1 (IGF-1) and its binding protein 3 (IGFBP3) was associated with a lower risk of worse frailty status four years later. "Vitamin D, besides maintaining bone health, regulates muscle function, and...
  30. Nelson Vergel

    Fat and Meat Intake Increased IGF-1 in Men

    Dietary Fat and Carbohydrates Are Independently Associated With Circulating Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor–Binding Protein 3 Concentrations in Healthy Adults Journal of Clinical Oncology 17, no. 10 (October 1999) 3291-3298. PURPOSE: To evaluate and quantify the...
  31. Nelson Vergel

    Vitamin C in Citrus Fruits Increase IGF-1 in Women

    "In conclusion, we found that women with higher intakes of citrus fruit and dietary vitamin C had higher circulating concentrations of IGF-I and lower concentrations of IGFBP-3. These results raise the possibility that higher intake of this fruit subgroup and its vitamin C constituent may be...
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