health

  1. madman

    LifeMD Announces Exclusive Collaboration to Launch Direct-to-Patient Self-Pay Program for XYOSTED® (testosterone enanthate) Injection

    * The program will launch in July 2026 and will initially be available in 37 states. * Life MD’s platform is designed to remove those barriers by combining clinically appropriate virtual evaluation, lab-based diagnosis, ongoing clinical support, and access to home delivery of an FDA-approved...
  2. madman

    Marius Pharmaceuticals Applauds FDA’s Proposed Testosterone Labeling Updates as a Turning Point for Men’s Health

    https://mariuspharma.com/news/marius-pharmaceuticals-applauds-fdas-proposed-testosterone-labeling-updates-as-a-turning-point-for-mens-health/ The FDA’s second major labeling update in 16 months — after its February 2025 removal of the cardiovascular boxed warning — marks a historic...
  3. madman

    Associations of testosterone, SHBG, and related hormones with risks of cancer death, incident cancer, and incident prostate cancer

    In conclusion, men with lower testosterone concentrations had higher risk of cancer death, and men with mid-range SHBG or luteinising hormone concentrations had lower risk. Low testosterone concentrations were associated with risk of any fatal or non-fatal incident cancer. Men with lower SHBG or...
  4. madman

    Ozempic, GLP-1s and the Future of Obesity - Prof. Carel Le Roux

    Carel le Roux is a Professor of Experimental Pathology at University College Dublin, Director of the Metabolic Medicine Group, and one of the world's leading researchers on how the gut communicates with the brain. He completed his PhD at Imperial College London, where he conducted foundational...
  5. madman

    Shalin Shah - Revolutionising Testosterone Replacement Therapy

    In this episode, Shalin Shah, CEO of Marius Pharmaceuticals and a passionate advocate for testosterone education, shares insights on the misunderstood hormone that impacts both men and women. We dive into myths, testing protocols, treatment options, and the importance of early diagnosis for...
  6. madman

    New Research from Marius Pharmaceuticals Reveals Major Men's Health Awareness Gap: 65% Have Never Had Their Testosterone Levels Tested

    * The survey found that the most commonly reported symptoms over the past year (among those tested) included low energy or fatigue (48%), poor sleep (47%), reduced motivation (34%), low sex drive (28%), mood changes or irritability (27%), brain fog (26%), weight gain (26%), and reduced muscle...
  7. madman

    Predicting Circulating Testosterone Concentrations in Individual Men

    * We devised a formula to calculate predicted total testosterone concentrations, based on meta-analyses of individual participant data from 21,074 men, aged 17-99 years, from nine cohort studies in Australia, Europe and North America of community-dwelling men with testosterone measured using...
  8. madman

    Jessican Colon-Franco (Cleveland Clinic) ICP-MS testimonial

    * Dr. Jessica Colon-Franco is inspired by providing answers to physicians and patients using mass spectrometry. Dr. Jessica Colon-Franco is the Section Head of Clinical Biochemistry and Medical Director of the Special Chemistry Laboratory at Cleveland Clinic. Her clinical laboratory...
  9. madman

    U.S. Department of Health and Human Services through the FDA Requested Updates to Testosterone Therapy Product Labels

    https://www.hhs.gov/press-room/fda-requests-updates-testosterone-therapy-labeling.html The U.S. Department of Health and Human Services, through the U.S. Food and Drug Administration (FDA), announced today that it is requesting updates to the prescribing information for testosterone...
  10. madman

    VO₂max: The Fifth Vital Sign

    VO₂max is the most important metric of your overall cardiorespiratory fitness. It’s a measure of the maximal ability of your body to take in and use oxygen. But what does the number actually mean for your health and longevity? Why is it important to know your VO₂max? What’s the most effective...
  11. madman

    What a Cardiac CT Actually Shows. | Explained by a Doctor Who's Read 100,000 Scans

    * Clear Heart was built to solve that problem, offering direct-to-consumer self-pay access alongside physician referrals, with no 6-week hospital wait and results within 24 hours What does a cardiac CT scan actually show? In this video, Dr. Matthew Budoff - Professor of Medicine at the...
  12. madman

    Enclomiphene Explained: Is It Better Than TRT?

    19:11 Why Enclomiphene Is So Unpredictable * the response is widely variable! Enclomiphene has quietly become one of the most prescribed men's health medications in America. It's marketed as the perfect alternative to testosterone replacement therapy (TRT): an oral medication that increases...
  13. madman

    Individualized TRT demonstrates broad symptom improvements beyond sexual function

    Start low and go slow, where have we heard that one before LOL! https://www.contemporaryobgyn.net/view/individualized-trt-demonstrates-broad-symptom-improvements-beyond-sexual-function Testosterone replacement therapy (TRT) in women may offer multidimensional symptom improvement...
  14. madman

    NEW DRUG RELEASE CANADA: JATENZO®: Oral T replacement therapy

    https://canadianhealthcarenetwork.ca/new-drug-jatenzo-oral-testosterone-replacement-therapy
  15. madman

    NAD⁺ Boosters – New Insights into Their Differential Modes of Action in Humans

    Stefan Christen, Metabolomics Researcher at Nestlé Research in Lausanne, Switzerland, presents " NAD⁺ Boosters – New Insights into Their Differential Modes of Action in Humans" at Longevity World Forum 2026. Conclusion & Take-home message
  16. madman

    Strength Training for Everybody! Stuart Phillips on the new ACSM Strength Training Position

    Our co-host Stuart Phillips was the senior author on the ACSM’s gold-standard strength training position statement, a.k.a. “the most comprehensive evidence-based guidance to date on how resistance training supports muscle strength, muscle size (hypertrophy), power, and physical performance...
  17. madman

    Understanding the Peptide Movement in Men’s Health, with Larry Lipschultz, MD

    In this episode of Pearls & Perspectives, Amy Pearlman, MD, is joined by Larry I. Lipschultz, MD, to discuss the growing interest in peptides, including their potential applications in men’s health, evolving regulatory landscape, and what urologists need to know as patient demand continues to...
  18. madman

    The interplay between testosterone and depression: bridging research, clinical applications, and health

    * Overall, the available evidence suggests that TRT may provide clinically meaningful improvements in mood for hypogonadal men, particularly those with low baseline testosterone and coexisting depressive symptoms. However, current data do not support its routine use as an antidepressant therapy...
  19. madman

    Pictures are Worth a 1000 Words: Role of Imaging in CV Risk Assessment

  20. madman

    The FDA has granted clearance to Revvity’s automated chemiluminescence immunoassay (ChLIA) for total testosterone measurement

    https://www.urologytimes.com/view/fda-grants-clearance-to-total-testosterone-assay The FDA has granted clearance to Revvity’s automated chemiluminescence immunoassay (ChLIA) for total testosterone measurement.1 The assay is designed to support diagnostic testing for androgen-related disorders...
  21. madman

    Testosterone Levels Improve in Men under GLP-1 Receptor Agonist Therapy

    Dr. Andres Guillen Lozoya discusses findings from, "Testosterone Levels Improve in Men under GLP-1 Receptor Agonist Therapy.” This study aimed to evaluate changes in total and free testosterone before and after GLP-1RA therapy in men
  22. madman

    Obesity Scientist Exposes Calories: "This Is Why You Can’t Lose Weight!”

    Professor Giles Yeo MBE is a Professor of Neuroendocrinology and author of 'Gene Eating' and 'Why Calories Don't Count.' He joins leading men's health specialist Dr Jeff Foster in the Man Alive studio to combat popular myths surrounding weight loss, Ozempic, calorie-counting and fad diets. In...
  23. madman

    Holistic approach to male LUTS

    Speakers: Prof. J-N.L. Cornu (FR) Dr. M. Tutolo (IT) Dr. D. Elterman (CA) M. Creta, Naples (IT) This recording explores a holistic, patient-centred approach to male lower urinary tract symptoms (LUTS) beyond single-symptom treatment strategies. Male LUTS are common, heterogeneous, and...
  24. madman

    What You Don't Know About Testosterone

    Shalin Shah explains how testosterone serves as a key biomarker for overall health and outlines common symptoms that indicate testing is needed: including fatigue, muscle loss, and decreased libido. He emphasizes that while lifestyle factors like diet, sleep, and exercise are foundational...
  25. madman

    FDA Moves to Permanently Close the Door on Compounded GLP-1s (semaglutide, tirzepatide, and liraglutide)

    The agency's proposal to exclude semaglutide, tirzepatide, and liraglutide from the 503B Bulks List signals that large-scale compounding of these agents has no regulatory future, and carries immediate implications for pharmacy practice. The FDA has announced that it is proposing to formally...
  26. madman

    Sun Pharma signs Definitive Agreement to Acquire Organon

    Mumbai, India, April 27, 2026 and Jersey City, New Jersey, April 26, 2026 – Sun Pharmaceutical Industries Limited (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: SUNPHARMA, BSE: 524715) (together with its subsidiaries and/or associated companies, “Sun Pharma”) and Organon & Co. (NYSE: OGN)...
  27. madman

    Protein and Muscle Health

    * Dr. Phillips has published hundreds of scientific papers in this area, and his work has played a major role in shaping current thinking on protein requirements, muscle health, aging, and resistance training. In this episode, Brendan is joined by Dr. Stuart Phillips, one of the world’s...
  28. madman

    Higher Testosterone for Postmenopausal Women on HRT? Study Suggests ~78 ng/dL Total Testosterone Target

    Abstract INTRODUCTION AND OBJECTIVES: Testosterone replacement therapy (TRT) is an established treatment for hyposexual desire in postmenopausal women, yet the broader effects of TRT on menopausal symptoms remain uncertain. Our research aims to define optimal testosterone levels for symptomatic...
  29. madman

    Start ED Meds Early: PDE5 Inhibitors Within 1 Month Linked to Lower Heart Risk and Mortality

    Abstract INTRODUCTION AND OBJECTIVES: Phosphodiesterase Type 5 (PDE5) inhibitor is effective in treating erectile dysfunction and is generally safe concerning cardiovascular (CV) risk profiles. We analyzed hazard ratio and 1-year outcome of major adverse cardiac events (MACE) to depending on...
  30. madman

    Daily Cialis (Tadalafil) After ED Diagnosis: Lower Risk of Heart Events and Death Over 3 Years

    Abstract INTRODUCTION AND OBJECTIVES: Phosphodiesterase Type 5 (PDE5) inhibitor is effective in treating erectile dysfunction and is generally safe concerning cardiovascular (CV) risk profiles. We analyzed risk ratios and outcome of major adverse cardiovascular to depending on different period...
  31. madman

    Male Infertility Warning: High 17-OHP Levels Linked to Lower Motile Sperm Count

    Abstract INTRODUCTION AND OBJECTIVES: Early studies evaluating the role of 17-hydroxyprogesterone (17-OHP) in male reproduction were primarily conducted in fertile men receiving exogenous testosterone with varying doses of human chorionic gonadotropin (hCG). However, few studies have...
Back
Top