health

  1. madman

    ViraLite: an ultracompact HIV viral load self-testing system with internal quality control

    In conclusion, ViraLite demonstrates a sensitive, portable approach to self-directed HIV VL monitoring enabled by multiplex RT-LAMP, machine-learning–based fluorescence analysis, and semi-automated, battery-powered electronics. The system integrates sample preparation, multiplex detection, and...
  2. madman

    In Memoriam: Christina Chung-Lun Wang, MD (1944–2026)

    Huge loss! True trailblazer in the field. * Dr. Wang was internationally recognized as one of the world’s foremost authorities in male reproductive medicine and biology. Her pioneering research advanced the development of hormonal male contraception, androgen replacement therapies, treatments...
  3. madman

    20 years with NIHR: Professor Waljit Dhillo

    * Professor Waljit Dhillo is globally recognized as a pioneer in translating kisspeptin research from the laboratory to human clinical medicine. Over more than two decades, his team at Imperial College London has transformed our understanding of how this master hypothalamic peptide can be used...
  4. madman

    Don't Sleep on OSA: The Importance of Not Relying on Disease Severity in Making Treatment Decisions

    Apnea-hypopnea index (AHI) alone may not capture the full burden of obstructive sleep apnea (OSA). Explore how symptoms, quality of life, hypoxic burden, and individual risk inform treatment decisions.
  5. madman

    Update on testosterone deficiency and therapeutic options for testosterone replacement therapy

    Fig. 1 | Hypothalamic–pituitary–gonadal axis regulation. Abstract Testosterone deficiency, or male hypogonadism, is a clinical syndrome characterized by the presence of clinical features with persistently low serum testosterone levels. Testosterone deficiency is an important health concern...
  6. madman

    Testosterone, Testosterone Replacement Therapy, and Cardiovascular Disease

    * Low endogenous testosterone is consistently associated with higher all- cause and cardiovascular mortality but most plausibly marks multimorbidity rather than causation. * TRAVERSE established that physiologic transdermal testosterone replacement therapy was noninferior to placebo for 3-...
  7. madman

    No Growth Without Protein: Optimizing Anabolic Response In Older Adults

    Prof Yves Rolland, MD, PhD Professor of Internal Medicine and Geriatrics, Gérontopôle of Toulouse; Clinical Research Director, IHU HealthAge; University of Toulouse (France). There is currently NO DRUG to treat SARCOPENIA Take Home Message
  8. madman

    Androgen Sensitivity Is an Important Contributor to Treatment Response

    8th Annual Meeting of the Androgen Society 2026 presentations from the top experts in the field! Professor T. Hugh Jones Testosterone Cut Off Values from Guidelines CONCLUSIONS Hitting the nail on the head here! * The panel unpacks why “normal ranges” don’t fit every...
  9. madman

    Managing GLP-1 Side Effects and Endoscopy Risks

    Drs Benjamin Levy III and Michael Camilleri discuss managing GLP-1 gastrointestinal adverse effects, preparing patients for endoscopy, and treating obesity.
  10. madman

    The effect of stress on testosterone and sexual function

    Hammered home numerous times on the forum over the years whether natty or on jacked up on T excess stress (physica/mental) can have a negative impact on sexual function! * Chronic psychological stress leads to sustained activation of the HPA axis and suppression of the HPG axis, contributing...
  11. madman

    Testosterone for women belongs in the female range

    * Even at female doses, safety data stop at about two years. At male-range levels there is not a single safety trial. Nobody selling a woman a 500 can tell her what it does to her heart or her breasts over ten years. * A woman’s endocrine system is more delicately tuned than the finest Swiss...
  12. madman

    Treatment of Erection Disorders: Where We’ve Been & Where We’re Going

    Helen L. Bernie, DO, MPH, Director, Sexual and Reproductive Medicine and Assistant Professor of Urology, Indiana University, Carmel, Indiana, reviews what the 2018 AUA erectile dysfunction guideline got right, where evidence limitations created “gray areas,” and what still applies in clinical...
  13. madman

    Hims Expands Testosterone Care with Injectable and Oral TRT, Its Largest Men’s Health Launch to Date

    https://investors.hims.com/news/news-details/2026/Hims-Expands-Testosterone-Care-with-Injectable-and-Oral-TRT-Its-Largest-Mens-Health-Launch-to-Date/default.aspx Starting today, Hims is closing that gap, providing eligible customers access to three new treatment options, including: Two...
  14. madman

    The Role of Dihydrotestosterone (DHT) in Andrology

    8th Annual Meeting of the Androgen Society 2026 presentations from the top experts in the field! Dr. Michael Zitzmann Target organs of testosterone and its metabolites The Bifurcation of Testosterone: Amplification vs Aromatization The 5a-Reductase Distribution Map...
  15. madman

    SynAIRgy: The First Pill for Sleep Apnea? A Phase 3 Trial of AD109

    * This randomized, double-blind, placebo-controlled trial evaluated AD109, an investigational combination of aroxybutynin and atomoxetine, in adults with obstructive sleep apnea who could not or would not use positive airway pressure therapy. AD109 improved the apnea-hypopnea index and measures...
  16. madman

    Protein, Muscle & Ageing — What the Science Really Says

    38:00 Protein in everything — the hype that disappoints Stuart What really happens in your muscle when you eat protein? How much do you actually need? And what have 30 years of research changed about how we think about plant proteins? Stuart Phillips answers it all. In this Proteinology...
  17. madman

    Minimally Invasive Surgical Treatments (MISTs) for BPO: Which One to Choose?

    This recording, organised by the European School of Urology and the EAU Section of Functional Urology, explores the evolving landscape of Minimally Invasive Surgical Treatments (MISTs) for Benign Prostatic Obstruction (BPO). The scientific programme will focus on the following aspects: •...
  18. madman

    Renal Denervation for Uncontrolled Hypertension

    In this excerpt from Tall Rounds®, Luke Laffin, MD, provides an overview of the science behind denervation and significant clinical trials.
  19. madman

    Testosterone for Women: The Benefits Go Far Beyond Libido

    In this episode, Dr. Brandon & Dr. Morgentaler talk about why low testosterone can be overlooked in men experiencing fatigue, reduced stamina, and other changes often attributed to aging. They also discuss new research on testosterone therapy for women, why its benefits may extend beyond...
  20. madman

    Physiotherapy Rehabilitation Strategies for Prostate Cancer Survivors

    Pelvic Floor Muscle Training (PFMT) Electro-Acupuncture (EA) for UI Magnetic Stimulating Chair HIFEM/Emsella Key Takeaways
  21. madman

    Effects of oral fenugreek-derived preparations on testosterone-related outcomes in adult men

    https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1903508/full The current evidence does not support claims that fenugreek can reliably or clinically meaningfully increase testosterone (7–9). For users and clinicians, the most appropriate summary is that randomized...
  22. madman

    Hegseth's Testosterone Plan: A Doctor Who Treats Veterans Responds

    19:43 What an 'optimal' testosterone level really is Dr. Mark Gordon * Optimal health is between the 50th and 75th percentile of the range The average man today is walking around with meaningfully less testosterone than his grandfather had at the same age — and the fix the military is...
  23. madman

    Hypogonadism - Myths and Realities

    Learning Objectives HPG Axis Physiology Key TTh Takeaways https://www.adventhealth.com/institutes/research/team/john-tillet-md-1939
  24. madman

    Breaking the Cycle: The Power of Hormones

    Watch the full show: Dr Louise Newson's Breaking the Cycle: The Power of Hormones. Menopause, HRT and hormone health explained by the UK's leading women's hormone specialist. Free to watch. Recorded live in Nottingham, this is the complete theatre show from Dr Louise Newson's 2026 tour. It...
  25. madman

    Ceramide Risk Score: How to Incorporate it Into Your CV Prevention Practice

    Guest: Vlad Vasile, M.D., Ph.D.Host: Stephen L. Kopecky, M.D. Ceramides score is a blood test used to assess the risk of heart attacks and stroke. Most patients evaluated for cardiovascular risk benefit from this test, particularly patients deemed at intermediate risk by other assessments...
  26. madman

    ED Predicts Heart Attacks Better Than Chest Pain: The 2 Tests to Ask For

    Dr. Tobias Kohler * There T level at that point when they are healthy is a very important number. Most of the time it is going to be 500 or so, right? There are some published T levels per decade of life and it does go down. It's pretty rare to get above 1000 naturally considering that as a...
  27. madman

    Clinical Practice Guideline: Testosterone Deficiency in the Male Service Member

    https://www.dha.mil/HHPO The Department remains focused on building and maintaining a ready, lethal fighting force prepared to dominate the battlefield and achieve peace through strength. In his July 15, 2026, memorandum, "Health and Human Performance Optimization to Enhance Military...
  28. madman

    New Pavlov Study Could Help Sleep Apnea Patients Rest Easier

    Obstructive sleep apnea (OSA) is a condition that affects millions globally, causing daytime sleepiness, lack of oxygen, and higher risks of developing cardiac issues. A new randomized control trial, called the Pavlov study, evaluated the efficacy and long-term conditioning effects of a...
  29. madman

    Reviewing the evidence about testosterone in women

    https://www.contemporaryobgyn.net/view/reviewing-the-evidence-about-testosterone-in-women Before prescribing testosterone, know what the evidence actually proves. Maria Uloko, MD, draws a sharp line between the one population the data supports and the much wider group of women asking about it...
  30. madman

    Testosterone Use in Menopausal Women

    Why testosterone measurement is difficult in women What should be. measured? Normal range, reference range/interval. decision limit Join the FDA Office of Women’s Health (OWH) and Center for Drug Evaluation and Research (CDER) for a public hybrid workshop on Testosterone Use...
  31. madman

    The Peptide Industry Explained by the Pharmacist & Attorney Fighting for Its Future

    In this episode of Fertility and Other F Words, Dr. Amy Pearlman and Dr. Larry Lipshultz sit down with Lee Rosebush, PharmD, JD, MBA to discuss one of the most rapidly evolving and controversial areas in medicine: peptides, compounding pharmacies, FDA regulation, and the future of personalized...

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