dht

Could someone help discern how to measure andractim. I have the standard name brand gel. My doc advised to take 4 clicks a day of a compounded cream at 125mg/ml. The pharmacy then decided that they cant/wont make it. So I got the andractim. I need help figuring out how to measure...

Hair loss is one of those things that can feel so isolating, especially for women. But trust me, you’re not alone, and it’s not your fault. I had an amazing conversation with Dr. Omer Ibrahim, a dermatologist who’s just as passionate as I am about breaking down the stigma and getting real...

It’s not quite as off-the-wall as it sounds. We know that as serum testosterone increases the 5α-reductase enzyme starts to saturate, leading to a reduced efficiency in DHT creation, illustrated thusly: Even so, with high testosterone a lack of DHT is not going to be a problem; there’s still...

For men out there like myself who struggle with easily crashing their E2 on an AI (even with microdoses), yet still experience high E2 symptoms (itchy, sensitive nips, bloating etc) can topical DHT be used to replace an AI? I’ve found that using topical DHT eliminates any E2 sides that...

Say what you like, but I want higher DHT! Deeper voice, manly chest hair, higher libido, and fortunately I am not prone to male-pattern baldness. What testosterone formulations help increase DHT? Is scrotal cream/gel/patch the only way? What else can help increase DHT? And perhaps more...

I've been on TRT for roughly 3.5 years now, with very limited results. I started and kept using Test E most of this time. In the honeymoon phase I had great symptom relief, however after 3 months almost all of those symptoms returned, I only felt better emotionally and mentally. Honestly I was...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220510/ https://pubmed.ncbi.nlm.nih.gov/6249575/

As we very well know T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone. Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones beneficial effects on (cardiovascular health, brain health...

I was wonderining what the appropriate DHT range is on TRT. Has anyone ever had an ideal range that they were happy at? Are there any links on this site for the appropriate DHT range:) ?

Been reading the forum for many months and finally registered to post a question that I have. Hoping someone here more knowledge can help me out and possibly share any experiences. Strongly considering taking on a journey of penis extending with extenders and pumps to add some size. I know I...

Join us for our 2-year anniversary episode! Host Chase Hendrickson, MD, from Vanderbilt University Medical Center; regular contributor Rich Comi, MD, from Dartmouth Hitchcock Medical Center; and male reproduction expert Mathis Grossman, MD, PhD, FRACP, from the University of Melbourne and Austin...

I have recently resumed using topical DHT. It has been a few years since I have last used it and the concentrations are now higher than before. Naturally, I was curious as to any implications this may have on prostate health. Research has uncovered some fascinating information...

The thread discusses the modulation of circulating free testosterone fraction during Testosterone Replacement Therapy (TRT) and its relationship with other hormones. Here are the main points from the discussion: Free Testosterone Fraction: The thread emphasizes the importance of the free...

Androgens are a key factor in acne pathogenesis. Lawrence Green, MD, FAAD discusses how hormones help drive the skin disease. How DHT and Androgens Drive Acne Formation Androgens are integrally associated with acne development. Acne originates in the sebaceous gland, which is under androgen...

Unraveling the Mysteries of Benign Prostate Hyperplasia: Insights from Recent Research Benign Prostate Hyperplasia (BPH) continues to present challenges in both understanding its underlying mechanisms and effectively treating its symptoms. Recent research, presented in a transcript from a...

Purpose Androgenetic alopecia (AGA) is the most common type of hair loss in humans, affecting self-esteem and emotional well-being. This study aimed to assess the safety and efficacy of VISPOTM, a standardized saw palmetto oil (2–3% β-sitosterol), in subjects with mild-to-moderate AGA...

Studies examining associations of circulating sex steroids with mortality risk in men show inconsistent results for testosterone (T), with limited data for dihydrotestosterone (DHT) and estradiol (E2). We aimed to clarify associations of sex steroids, sex hormone-binding globulin (SHBG), and...

Defy has a topical Dutasteride. Im considering giving it a try, anyone have experience with this? I dont have bad hairloss, just want to be preventative. Dont want to drop DHT systemically.

So I have been doing TRT for 15 years. For the past 6 months I have reduced my levels down to .3ml per week of 200 mg/ml Test Cypionate from Hikma (thru Kroger). The shots are always Subq. (Test results are below) I kept stepping down because of hair loss. I'm just about at 3 months using...

I seem to convert T to DHT. At mild-moderate doses of 100-150mg T cream/day, my DHT levels run around 200. T levels range from 650-800, E2 30, SHBG 30. I have no clinical signs or symptoms to the negative whatsoever. What is the short and long term impact of running such “high” DHT levels? HCt...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016457/ "These analyses were not prespecified and need confirmation in additional studies of other datasets. Our models were modestly predictive, with r-squared values ranging from 0.16 for HDL cholesterol to 0.27 for vBMD, indicating that there...

I started a previous thread to unravel the mystery of why hCG improves libido in some men, which generated some good discussion but didn't reach any firm conclusions: https://www.excelmale.com/forum/threads/libido-hcg-vs-higher-t-e2.25785/ Now comes a youtube video from Cortex Labs that claims...

Hi everyone, I have been following this board for some time now and was looking to get some opinions on my situation. I am 35-year-old male suffering from post-finasteride syndrome for the last 15+ years. My symptoms are mostly sexual: mild ED, decreased EQ and decreased sensitivity. Below are...

Finasteride and dutasteride, known as 5-alpha reductase inhibitors (5ARIs), are used to treat benign prostatic hyperplasia and androgenetic alopecia. These drugs block the conversion of testosterone to dihydrotestosterone, which affects the neuroendocrine system. They have potential applications...

The pharmacological regimen increased E2 levels for more than 24 hours, affecting the HPG axis, LH, FSH, P4, TST, DHT, SHBG, and IGF-1. While E2 had similar effects to longer-term treatments, SHBG levels did not increase. TST and DHT changes could confound the effects of E2. These hormones have...

So my doc let me change my protocol, I dropped down to 12mg a day , and apply 1 click of test cream which is 12.5mg to the scrotum area. My DHT came back way over range, My TT and FT are about the same as doing 14mg daily that I was doing. The only thing is erection quality went down the drain...

https://www.sciencedirect.com/book/9780128216767/human-gonadotropins#book-description Gonadotropins and steroidogenesis (2022) Estrogens and progestogens The sex steroids are androgen, estrogens, and progestogens. They are all made from the root steroid cholesterol (Fig. 14.1). Cholesterol...

Hello, Does anyone know if cialis and metformin stops or makes rogaine/minoxidil less effective for hair regrowth? Metformin decreases pge2 level: https://www.frontiersin.org/articles/10.3389/fonc.2017.00243/full https://www.nicehair.org/increase-scalp-pge2-decrease-pgd2-cure-hair-loss/

I’m seeing a lot more post with people who have test levels above 1000 who feel crappy. Even with everything else in range e2, DHT, prolactin etc. I’ve also have seen post of people almost using microdose amounts and feeling way better. My question is, is this the new thing? Because my doctor...

So I have been feeling pretty crappy lately (down depressed anxious and no libido) and decided to do labs. I had labs done and my t was -1319 E2 sensitive was - 31 Shgb- 42 Free T was 29 But the weirdest one was my dht it came in at 50pg/ml. Which is incredibly low. What makes no sense is I’m on...

Is Pygeum worth experimenting with? Libido is already an issue for me and I've been trying to improve it for ages. Since Pygeum decreases DHT I'm guessing it can have harmful effects on my libido. I did notice great effects from an alpha blocker - Doxazosin. Thoughts on adding Pygeum to the...