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For anyone taking an ARB like Losartan or an ACE (i.e. Lisinopril), there are a bevy of conflicting reports as to whether these meds are protective or facilitate coronavirus infection. PROS: Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics. - PubMed - NCBI Use of angiotensin...

Been on a LCHF (50-55% fats, 35% protein, 10-15% carbs) diet for several years. Euglycemic up to now, never been dx'd as T2D or pre, although I carry several genetic variants that predispose me to it. My post-prandial blood glucose (PPBG) levels are normal, rarely exceeding 125 as are my a1c...

I've been having a bad bout of PVCs this last week and cannot determine the cause. They seem to activate when either supine or standing. Sometime when standing up, I get near-syncope (lightheadedness). EKGs from urgent care visit definitely reveal PVCs. I do ok with moderate exertion (cardio)...

The consensus of opinion from most practitioners is to NOT take your med for at least 7 hours prior to lab draw. I had always taken my morning dose about 2 hours before draws and likely received misleading serum levels until I recently changed to taking my last dose about 15 hours prior to the...

For those interested, the struggle to find a U.S-based pharma grade supplier is now over. Tailor Made Compounding Pharmacy now offers it and licensed physicians can prescribe it: Box If anyone is already using it, please give us details, specifically, if it is nothing more than clomiphene...

One of my major goals for this year is to find ways to effectively recomp (drop bodyfat and retain lean mass or increase) for both wellness and cosmetic. In my case I need to lose ~ 30 lbs total while trying try to retain LBM and get to no more than ~16.5% bf. No small feat for me, especially...

Curious to know if anyone is using Tailor Made. They are one of the few FDA-regulated pharmacies that offer pharma-grade peptides: https://tailormadecompounding.com/about-us/ More from Jay's chat with Ryan@ Tailor Made: http://www.totrevolution.com/why-peptides-are-the-future-o…/

As we learn more about how elevated levels of Lp(a) can potentially kill us before anyone can determine the cause, it is imperative that everyone get this lipid marker tested frequently, especially those on any type of HRT regimen. It is entirely possible that one of the leading culprits behind...

Somewhere I read in the research that it is not a linear increase and FSH/LH will self-regulate T levels on matter the dose, but I can't find those studies now, but it still wasn't clear to me. Anyone know?

Still got a ways to go before FDA approval, but it looks like injections and gels will eventually become phased out with a TRT agent exhibiting a significantly lesser side effect profile that actually enhances HPTA, and most importantly, induces ENDOGENOUS production of both total and free T in...

Re-evaluating to move forward with TRT yet again (for those that are new or forgot, I have a clotting disorder of unknown origin, so I've held off on TRT because of the recent studies showing it can induce clots in prone individuals). Last labs showed Total T @ 610, not bad for my natural...

http://vimeo.com/97650724 Max Gotzler wasn’t feeling his best during a long German winter. He decided to visit his physician to see if anything might be going on. This included various blood and micronutrient tests. When he received his results he noticed that his testosterone levels were on the...

Anyone try Tetsofen and gotten good results? http://www.gencorpacific.com/index.php/featured-ingredients/testofen I am trialing it since, for now, straight T is contraindicated in me due to my history of thrombophilia (blood clots). I have been on it for 2 mos. and have noticed a tiny increase...

Something the Medical Orthodoxy wants to shun: https://app.box.com/s/vnfmdyohh8hkqwsxt7yd Testosterone Reduces Risk of CV Events

http://ajcn.nutrition.org/content/76/1/5/T1.expansion

Does anyone use this index to evaluate dosing and efficacy of TRT? My doc does. Need more data to fully understand this. http://www.bostonmedical.com.co/content/testosterone-and-free-androgen-index

If you've tried every possible diet - counting calories, keto, low carb, high protein, paleo, intermittent fasting - and every conceivable workout - and still get lackluster gains, not enough lean mass, and too much body fat, you're most likely not producing optimal hormone levels - - -...

Interesting blog from Adel Moussa on the diminishing returns of supraphysiologic doses of T (in this case test e): http://suppversity.blogspot.com/2012/01/intermittent-thoughts-on-building_02.html some highlights: "elevations and even reductions of testosterone levels within the normal...

http://suppversity.blogspot.com/2014/01/low-testosterone-low-life-expectancy.html "To quantify: You want to have your total testosterone levels in the 12.56 – 15.75 nmol/L (362ng/dl - 454ng/dL), your free testosterone levels in the 182.66 – 216.34 pmol/L (5.3-6.2 ng/dL)". These...

I keep hearing the same thing over and over from friends and others: that test cyp caused them excessive water retention and "bacne" , and when they switched to the same dose on test e, no more of either. I have a hard time figuring out why a simple change of just the ester would make any...

http://blog.lef.org/2013/06/can-niacin-fight-heart-disease.html Anyone else taking niacin to raise HDL, lower trigs and LDL? I am on 1500mg daily. Liver, homocysteine, FBG, so far, so good. This article mentiones doses in excess of that.

http://suppversity.blogspot.com/2013/11/treating-diabesity-with-testosterone-if.html?spref=fb

These data demonstrate that 6 months of GH administration in healthy older men elicits small but significant decreases in TT4 and reciprocal increases in TSH. In comparison, T supplementation in older men neither directly alters, nor modifies the effects of GH, on serum TT4 or TSH. Whether GH...

http://thedailynewsonline.com/lifestyles/article_77a0170c-ca16-58df-8359-3db8c09dae8a.html Both too little E2 and too much E2 = fat gain.

Soy lecithin is a ubiquitous ingredient used in many protein powders and other supplements. As we know, soy protein itself is estrogenic, but is soy lecithin? The research I've seen is scant on whether it does or not, but one thing I do see is more supplement makers using sunflower or canola...

Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels http://jama.jamanetwork.com/article.aspx?articleid=1764051 "The absolute rate of events were 19.9% in the no testosterone therapy group vs 25.7% in the testosterone therapy...

Anyone have a clue why E2 keeps dropping??? SHBG actually dropped a little (39). I have eliminated what I thought would be causing a drain on E2 (calcium-d-glucarate). TRT still on hold for now. Upping DHEA to 50mg/day. My guess is that my long term use of T3 (which increases SHBG) has crippled...

The benefits of TRT in CV health: http://www.heartfixer.com/CHC%20-%20Treatments%20Available%20-%20Pellet%20Therapy.htmtrt

Anyone ever had any experiences they can share with either of them?

All those idiots telling us to reduce unprocessed SFAs are living up to their title as just that - IDIOTS. In fact, I recall my Lp(a) being its lowest when I was eating lots of whole eggs and coconut oil. Low-fat high carb diets are proving more and more to simply be unhealthy all around. My...

So, what if your average TT is 500? Is TRT automatically warranted? http://defymedical.com/resources/blog/191-total-testosterone-over-550-ng-dl-reduced-the-risk-of-cardiovascular-events