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I think the other day I may have taken too much AI and crashed my E2 cuz had numb cock and no libido and Viagra had almost no effect. 2 days later I took Estradiol blood test and Estradiol Ultrasensitive LC/MS blood test. The results… Estradiol = 21 (Range: < OR = 39) Estradiol Ultrasensitive...

I mean, I haven’t slept in 4 years without taking drugs. I’ve been on TRT for 4 years and I think that is why I cannot sleep well. When I started taking TRT I can only get about 4 hours of sleep. Then I wake up and I am wide-awake, but also tired. I cannot fall back asleep unless I eat a high...

Well someone had to ask. Seems like woman do better in survival rate. I read that testosterone has an immunosuppressive effect while estrogen has an immunoenhancing effect on the immune system. Estrogen has been shown to regulate immune response. This enhanced immune reactivity in females...

How do I measure what the correct dosage of T3 is right for me? Should I slowly increase my dose until my RT3 goes to normal level? Should it be based on TSH? Should it be based on body temperature and pulse rate (I am aware that my resting pulse shouldn't exceed 80 and body temperature 98.6)...

So far my experience with low carb/low calorie dieting (keto) is that it SEVERELY slows down your metabolism. Granted I’ve lost about 20 lbs but I am sure half of what I lost has been muscle. Currently I consume 1500 to 1600 calories per day. Go to the gym 6 days per week (for 26 years). Walk...

I noticed that actual endocrinologists who treat patients for elevated RT3 using Cytomel often prescribe T3 dosages between 10 to 15 mcg per day. Then I see other people who say they get 50+ mcg prescribed. How do you determine what dose to use? Is there a danger taking 25 or 40 mcg?

I don’t think I am aging too fast but I am 45 and I want to keep looking young as long as possible. Ive done a search on the board with not much or any results. Wondering if anyone here has tried Tretinoin long-term for anti-aging and whether they thought it was worth it. Like did it make you...

I am currently on a low carb, calorie restricted diet to lose weight. I have a good amount of muscle mass as I have been lifting weights for 26 years. I have about 15 to 20 lbs more to lose. I am 45 years old. When I am NOT dieting my TSH is about 3.40. When I am dieting my TSH goes up to 5.44...

I did a CBC and my hematocrit was 52. My hematocrit has always been a little elevated anyway. But can a very low carb keto diet cause enough dehydration to make your hematocrit/hemoglobin elevated? The CBC doesn’t show BUN/CREATINE RATIO (I think that measures level of hydration). So I don’t...

Before I started testosterone my erections were weak. Viagra was my best friend. When I started injecting testosterone my erections and libido increased. But is there a way to make it better? I keep hearing people say that high estradiol increases libido/erections. Other places say high...

Will sleep apnea alone cause clinically high Hematocrit? If so, will a CPAP machine lower it? I don’t know that I actually have sleep apnea but I will be getting tested in 2 weeks. But even before TRT I had borderline/clinically high Hematocrit, at least since 2013. Before that it was normal...

In general does elevated estrogen from TRT cause acne?

Hey guys. I’ve been weightlifting for 26 years religiously. Currently I am 215 lbs and trying to get to 195 lbs. I’ve already lost 15lbs. My problem is I am trying to maintain my muscle while just losing fat. I am always obsessed with making sure I get enough protein that I think it prevents me...

If someone has a total testosterone of 150 but their free testosterone is within range, do they have low T? That was my case before I started TRT. I had clinically low total testosterone but my free testosterone was within range (but maybe on the lower end of the scale). So if someone has a...

I have seen people say that studies suggest Metformin raises SHBG but I haven’t seen anyone say that Metformin actually raises SHBG through their own experience. My SHBG ranges from 8.9 to 11. Has anyone seen their SHBG raise as a result from taking Metformin?

By looking at my thyroid lab bloodwork what does the following tell you? Does it mean that my metabolism is sluggish? The only thing out of rage is TSH. I am on 15mcg of Cytomel. TSH = 5.060 RT3 = 19.9 T3 Free = 3.7 T4 Free = 1.37 Here are my lab results prior to Cytomel were: TSH = 5.740 RT3...

Hello! I’ve heard people say that if you have low SHBG that more frequent injections are better. What is considered more frequent injections, ED or EOD? My SHBG is 12. Can someone say for sure there is a measurable difference between the ED and EOD? For example, did free T go up even more?

On two different blood test my TSH was over 5.4 so I scheduled an appointment with my GP. Kinda afraid he’s not knowledgable on the subject, or maybe he is. But I was wondering if anyone wants to give their input so that maybe I go to the doctor better informed. Based on my results, should...

Hello! Before I started TRT recently I discovered my TSH was high (5.44) and I had TPO antibodies present. Which I guess would signify Hashimoto’s. Anyway, I just took another TSH test and antibodies test to see if it improved since starting TRT. Should get results later. But my questions is...

Can anyone tell me what T3 uptake means? I took a TSH test and it was 5.20. I then took a complete TSH test a week later and my numbers are as follows: Free T4 Index (T7) 2.7 - Range 1.4-3.8 T4, Free 1.4 - Range 0.8-1.8 T4 (Thyroxine), Total 7.2 - Range 4.5-12.2 T3, Total 97 - Range 76-181 T3...

TRT can be a little expensive. But it would be very affordable if I can use a GoodRX coupon. Are these coupons legit or a gimmick? I seen a coupon that would save me $274. Anyone have trouble using them for test?

Hello. I’ve taken brand name Testim 1% before cuz I would get free samples. But now that the free samples have run out I would have to buy it. However it’s way to expensive (like almost $400 without insurance). Are there cheaper versions? I was considering going to a local compounding pharmacy...