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  1. Seagal

    Peptide suppliers

    What about peptide suppliers in the EU?
  2. Seagal

    Test cyp 6 months - still can't dial in

    Maybe best to stop the trt experiment. Imho the bit more T YOU get from trt is unlikely to make a significant difference in muscle gain. Brain fog can have many causes...
  3. Seagal

    Variable-resistance training

    Do you take your own equipment (chains, bands) to the gym or is it already available? I haven't seen anyone in my gym using it with machines or free weights.
  4. Seagal

    Variable-resistance training

    Has anyone experience with variable-resistance training?
  5. Seagal

    Test cyp 6 months - still can't dial in

    Before TRT no ED and normal libido? Brain fog gone with Estradiol and Prolactin now at higher end? With your high FT you could further reduce the dose, and split your dose to 3x/week.
  6. Seagal

    Feminism and male testosterone

    Something is happening to men, and no one is talking about it. Child attachment and parenting expert Erica Komisar reveals how modern society is rapidly stripping men of their traditional roles, leaving many feeling lost, directionless, and disconnected from both their families and their...
  7. Seagal

    Second Opinion on Restarting TRT (Primary Hypogandism)

    You mentioned E2. Where was/is E2 on/off TRT?
  8. Seagal

    TRT vs Clomiphene: Effect on IGF-1

    What Nelson posted: " Magnitude matters clinically Even the largest falls with SERMs kept IGF-1 within the adult reference range in most subjects, so frank GH-deficiency symptoms were not seen. Testosterone-related rises were modest; reaching the upper-normal IGF-1 range is uncommon at...
  9. Seagal

    Estradiol 230 pmol/L too high?

    Wonder what her plan is. TT of 40? You could ask her! Your FT is already very high. Imo you should rather reduce and split the dose.
  10. Seagal

    Please tell me how vitamin D supplementation has caused calcium deficiency, let's discuss.

    AI: 1. The "Muscle Meat Only" Carnivore: This is the biggest risk. Someone who eats only steak and ground beef with no sources of dietary calcium (no bones, no dairy) is at high risk for a negative calcium balance. The body will maintain blood calcium by increasing PTH, which will pull calcium...
  11. Seagal

    What's the u-shape for estrogen?

    We get three hormones with TRT and strangely their ratios are not the same with topical, oral, injection and with different esters or IM, SC.
  12. Seagal

    Please tell me how vitamin D supplementation has caused calcium deficiency, let's discuss.

    What my AI thinks The core of your problem almost certainly lies in the interplay between Vitamin D, Magnesium, and Parathyroid Hormone. · Most Likely Scenario (90% Confidence): You have an underlying magnesium deficiency. Supplementing Vitamin D exacerbates this deficiency, leading to impaired...
  13. Seagal

    Need honest advice: Do I really need TRT? Low-normal T, low libido for years, anxiety/OCD background, little muscle growth

    Regarding your concerns about fertility, you could search the forum for oral testosterone. I have no experience with it but that's what I would use (if I had access to it) to start or try TRT.
  14. Seagal

    Need honest advice: Do I really need TRT? Low-normal T, low libido for years, anxiety/OCD background, little muscle growth

    I asked my AI, it suggested you try TRT. Imo, it sounds multifactorial. It's difficult to give any advice. Do you have a problematic porn consumption?
  15. Seagal

    Lowering trt dose/ increasing frequency of injections question

    To me it makes no sense. Maybe some looking only at the trough level and chase a magic number.
  16. Seagal

    Lowering trt dose/ increasing frequency of injections question

    If you keep the weekly T dose constant and increase the injection frequency, it will flatten the curve, i.e. it will reduce the peak and increase the trough T levels.
  17. Seagal

    Reaching orgasm

    Your T dose is probably too high. Is it 250mg/mL?
  18. Seagal

    Dihexa for Cognitive Enhancement

    Me neither. SLU-PP-332 did work for me but it is too expensive (EU).
  19. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    That's my experience (Proviron, Anavar) but I felt like I had to state that. Nandrolone was terrible for me, however, most guys encounter only benefits.
  20. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    Using tren or any other AAS (but T) alongside with psychiatric medications seems like a terrible idea. On the other hand there might be benefits: Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes - Excel Male Health Forum It might stop worsening of...
  21. Seagal

    Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

    Proviron, Masteron, Oxandrolone is not (significantly) converted by 3α-HSD. Tren is converted by 3α-HSD into the more potent Tren-3α-ol. 3α-HSD: 3α-Hydroxysteroid Dehydrogenase If SSRIs on TRT are still needed and one doesn't notice any of the supposed mental benefits of TRT, I would suggest...
  22. Seagal

    Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

    https://pmc.ncbi.nlm.nih.gov/articles/PMC23979/ "The enzymatic efficiency of the conversion of DHT to androstanediol increased 163-fold when the enzyme was incubated with fluoxetine and 63-fold with paroxetine but did not change substantially with imipramine. " Couldn't find follow-up...
  23. Seagal

    DHEA and Pregnenolone best times to take

    Haven't heard of such side effects. If there is an underlying anxiety issue then I think it's possible that it could be triggered because dhea can have a stimulatory effect. I would take it in the morning.
  24. Seagal

    Dihexa for Cognitive Enhancement

    Only knew Selank and Demax. Background information about AngII from deepseek: High-Level Summary Angiotensin IV (Ang IV) is a small peptide fragment (6 amino acids) derived from the larger Angiotensin II. For decades, it was considered an inactive metabolite. However, research has shown that...
  25. Seagal

    Help me make up my mind about a change in protocol

    Now I understand what you meant by SC is not working for you.
  26. Seagal

    Help me make up my mind about a change in protocol

    What's the difference in serum levels? Could you adapt the subq dose to match the IM levels? You could apply the cream to your shoulders. Another option is oral TU.
  27. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    For me nandrolone was terrible even at a low dose. Currently the full name of tren is replaced by * indicating that it has no place in trt/hrt. Maybe it was never considered at very low dosages to supplement trt. Since on TRT, my impression is that I have more visceral fat relative to...
  28. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    You are right. I think the Ctrl group should represent the healthy population. The high fat high sugar diet group represents the metabolic syndrome. .... With MetS and TD, tren showed benefits over test.
  29. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    Vigorous Steve did research on this. For his body weight/composition about 25mg per week. I was looking into tren hex (Parabolan) bc of its long halflife. At low dose tren could work as sarm without spill over, i.e. sarm with anabolic and androgenic activity at muscle, fat, brain tissue. Maybe...
  30. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    https://academic.oup.com/endo/article/157/1/368/2251856 "We propose that TEST replacement therapy may have contraindications for males with TD and obesity-related MetS. TREN treatment may be more effective in restoring androgen status and reducing cardiovascular risk in males with TD and MetS."...

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