Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

Seagal

Well-Known Member

"We propose that TEST replacement therapy may have contraindications for males with TD and obesity-related MetS. TREN treatment may be more effective in restoring androgen status and reducing cardiovascular risk in males with TD and MetS."

TRT plus tren micro dose as add-on?
 
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"We propose that TEST replacement therapy may have contraindications for males with TD and obesity-related MetS. TREN treatment may be more effective in restoring androgen status and reducing cardiovascular risk in males with TD and MetS."

TRT plus tren micro dose as add-on?
********** is one of very few compounds that seems to specifically remove visceral fat. There would need to be data on what dose/duration starts to present kidney risk before using it long-term in humans however the doses used in the physique community are likely wildly excessive for the purpose described here.
 
According to the study, it doesnt seem like Tren reduced fat or promoted muscle much more than the control, unless I am reading the graphs wrong....
 
********** is one of very few compounds that seems to specifically remove visceral fat. There would need to be data on what dose/duration starts to present kidney risk before using it long-term in humans however the doses used in the physique community are likely wildly excessive for the purpose described here.
Vigorous Steve did research on this. For his body weight/composition about 25mg per week.
I was looking into tren hex (Parabolan) bc of its long halflife.
At low dose tren could work as sarm without spill over, i.e. sarm with anabolic and androgenic activity at muscle, fat, brain tissue. Maybe better than exogenous DHT for some persons.
 
According to the study, it doesnt seem like Tren reduced fat or promoted muscle much more than the control, unless I am reading the graphs wrong....
You are right. I think the Ctrl group should represent the healthy population. The high fat high sugar diet group represents the metabolic syndrome. .... With MetS and TD, tren showed benefits over test.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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