How did this feel? I would think this, with some daily hCG added to bump the numbers up a little and fill in some gaps, ought to be a decent protocol for you.
Look at you! Very impressive sir - not much room for improvement here. Still, give the 5/8" needles a shot (hah) if you ever return...
You don't care about E2 numbers but are trying very hard to keep your E2 at a specific number. Got it.
No, I've never seen it used for this purpose before. Metformin is a cutting edge adjunct in the TRT space. Let us know what happens if you try it.
I would suggest the second statement follows from the first. Excessive E2 has anti-dopaminergic effects via at least three distinct mechanisms: disinhibited prolactin release (prolactin reduces DA synthesis and firing), downregulation of D1 and D2 receptors, and a serotonin/GABA crosstalk...
I concur with the others: I would restart with T alone, no hCG, no AI. The prominence of the doctors you consulted with, and your weight, are immaterial with regard to how you should approach this to optimize your chances of success and health outcomes.
The difficulty of dialing in rises in...
It's probably fine for many purposes as a TRT adjunct. My friend is only able to use .25 ml of the alphagels product every other day because it's so potent, and testing suggests that is only ~10% DHT.
Your only hope of dialing in anastrozole is frequent bloodwork, and even that can be misleading, as the blood levels of E2 don't necessarily correspond to the effects of aromatase inhibition in tissues. Without the bloodwork though, your already low chance of success is reduced to pretty much...
I'm doing it - taking 150 iu daily right now, and if I have to drop something lower, it will be the testosterone.
That's a far cry from running hCG alone or test suspension though, either of which will produce a 24 hr testosterone AUC that is somewhere close to my natty test AUC. Please don't...
The decay rate of her follicles is the determinant of ovarian failure and it doesn't seem to matter whether you are stimulating them and releasing them or not. Their lifespan seems relatively fixed and finite either way (and is only about half of the woman's lifespan, strangely).
I just read 4...
That's all pretty normal. What you're missing that is really important here is SHBG, so you could calculate your free testosterone. You'll want to repeat the total T, and this time I would add SHBG, estradiol (ultrasensitive) and LH.
Free T is basically all that matters for hypogonadal...
That probably would work pretty well, but I'm not prepared to give up the physique advantages of actual TRT just yet. Maybe down the road if nothing else works.
Crucial point here. Giving my perimenopausal wife TRT only without estradiol did not work out well long-term. It gave her a strange mix of libido at times, combined with pain/discomfort during intercourse due to lack of estradiol.