Is my E2 high? It CERTAINLY feels like it!!!

leeault

New Member
Hi guys,


I'm from the Uk and there is NO SENSITIVE e2 test here at all - even to professionals!

My e2 on Nebido is 157 pmol/L but can that be any kind of marker fir a man? I think it converts to about 50 in USA measurements but is that reliable. I here some would say that is 10-20 over what is ideal

Should I try to lower it assuming it is more or less 50? I feel like I have a vagina and cry at things like Disny...I used to be a cage fighter for over a decade...this ISNt me.
 
If that indeed converts to about 50 on the standard test...ya it's kind of high. I know you UK guys don't have the sensitive test so I think you need to be particularly good with reading symptoms, which are clear indicators of high(er) Estrogen. My advise is if you treat it on your own go slow, if you have access to Anastrozole go small doses like .25mg per week and work up from there.
 
Many thanks for the reply Vince. First time I have actually ever got a response on this website!!

I'm sorry your previous posts went nowhere. We're certainly glad you joined EM. I live outside the United States as well, but in Canada. I'm able to pick up the sensitive e2 test in my own due to frequent border crossings. Given your situation, what does your doctor say when you raise the question of elevated estradiol? Are you taken seriously, or dismissed?
 
My E2 has repeatedly tested in the high 40's & I've had gyno since puberty & my docs don't seem to think it's a big deal. Main reason why I looking at 5th & 6th opinions. Any idea if grape seed extract, stinging nettle, zinc or anything else OTC will help?
 
My E2 has repeatedly tested in the high 40's & I've had gyno since puberty & my docs don't seem to think it's a big deal. Main reason why I looking at 5th & 6th opinions. Any idea if grape seed extract, stinging nettle, zinc or anything else OTC will help?

Those supplements typically do not help enough - by that I mean, say you take grape seed extract and it lowers your E2 by 2% (Just making this up as an example). If you have had gyno since puberty you are likely to need something stronger like Anastrozole. I would still start low and go slow, though. Its easy to get at research chem sites or places like http://www.safemeds4all.com/
 
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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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