Thanks
The insert is in Spanish and I don’t speak it. I have e mailed the manufacturer to ask them.
I get it ampoules are designed for single use but 250mg in one shot is too much for most people. Also enanthate comes in 250mg ampoules but as far as I can read it has Benzyl Benzoate which is preservative ?
I get it ampoules are designed for single use but 250mg in one shot is too much for most people.
Yes 250 mg T/week would be overkill.
Unfortunately as per manufacture instructions for dosing the majority are still caught up on those piss poor outdated protocols decades later.
Injecting a high dose of T once every 2 weeks.
This is why the strength/mL of the esterified T in the oily solution is so high as they were meant to be injected once every 2 weeks.
Standard recommendations would be injecting a high dose of T once every 2-4 weeks which clearly does not take advantage of the PK as this would result in a roller-coaster effect as in sky-high TT and more importantly FT 24 hrs post-injection/during the first 2-3 days followed by a slow decline over the following days and come day 10-14 levels will be much lower as in being back to hypogonadal.
This would have a negative impact on energy, mood, libido/erectile function and recovery due to wild swing from the very high peaks to much lower troughs.
Same can be said for injecting much higher doses once every 3-4 weeks.
As you should very well know the most commonly prescribed protocols used by those in the know is 100-200 mg T/week injected once or twice-weekly.
Standard starting dose across the board is 100 mg T/week or 50 mg injected twice-weekly.
Most men on T-therapy are injecting 100-200 mg T/week whether once weekly or split into more frequent injections as in twice-weekly (every 3.5 days), M/W/F, EOD or daily.
The majority of men can easily hit a healthy/high trough FT injecting 150 mg T/week especially when split into more frequent injections.
Yes there will always be those outliers who need the higher end therapeutic dose 200 mg T/week but it is far from common as in rare.
Such dose would have the majority overmedicated.
There are also those on the other end of the spectrum who can hit steallar levels injecting <100 mg T/week especially when split into more frequent injections.
Also enanthate comes in 250mg ampoules but as far as I can read it has Benzyl Benzoate which is preservative ?
This would sum up why some manufacturers use a preservative in single one time use ampoules.
* Some testosterone manufacturers include preservatives like benzyl alcohol in single-use ampoules to provide an extra margin against potential microbial contamination during manufacturing, filling, or brief handling before immediate use, despite the sealed glass design minimizing risks. Scientific studies on sterility show oil-based injectables can support bacterial growth if contaminated, prompting some formulations to incorporate antimicrobials for safety assurance, even in nominally single-use formats. Others omit them because rigorous aseptic processing and the inherent antimicrobial properties of oil carriers suffice for one-time use, aligning with USP guidelines that do not require preservatives in true single-dose containers.
Again the most recent package insert/leaflet 2025
Preservative free.
Package insert translation!
https://cima.aemps.es/cima/pdfs/es/p/27691/Prospecto_27691.html.pdf
Composition of Testex Prolongatum
The active ingredient is
testosterone cyclopentylpropionate. One ampoule contains 250 mg of testosterone cyclopentylpropionate (corresponding to 174.8 mg of testosterone) in 2 ml of solution.
The other components (excipients) are: ethyl oleate and olive oil.”
3. How to take Testex Prolongatum
Always use this medicine exactly as your doctor or pharmacist has told you. If you are not sure, ask your doctor or pharmacist.
Before starting treatment and during the first part of treatment, your doctor will measure your testosterone levels in the blood by means of a blood test. This will determine the dose of testosterone your doctor prescribes.
The usual dose of Testex Prolongatum is 1 ampoule by intramuscular injection every 2–4 weeks.
Testex Prolongatum must be administered only by intramuscular injection. It is recommended to inject it into the gluteal muscle. Care must be taken not to inject the product into a blood vessel.
If you think the effect of Testex Prolongatum is too strong or too weak, tell your doctor.
Use in children and adolescents
Testex Prolongatum is not recommended for use in children or adolescents under 18 years of age because of the lack of efficacy and safety data in this population.
If you take more Testex Prolongatum than you should
Symptoms of receiving too much Testex Prolongatum include irritability, nervousness, weight gain, frequent or prolonged erections. No special measures are needed, except stopping treatment or reducing the dose. Tell your doctor and he or she will tell you what to do.
In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately, go to the nearest hospital or call the Toxicology Information Service on 915620420, stating the medicine and the amount taken.
