Can we talk about low dose daily tadalifil

[stickersteve]

I am 67 and gave testosterone a shot earlier this year. I tried both shots and creams. Yes they raised my levels but I did not feel any better. In fact I felt worse. I saw a lot of posts here saying just to give it time, but I gave up on giving it time. I felt testosterone was a younger mans game, and it gets very confusing. I just want to keep things simple so I started researching low dost tadalifil (cialis) There are a lot of articles that say pretty much all men over 40 should be taking it for its prostate, heart, brain protection alone. There are very little if no side effects. Its cheap, and for me it works. I cant say for sure whether or not it is protecting my heart and brain, but I do pee more and wake up in the middle of the night/morning, pretty much every day with erections, and that had not happened in years. Even women can take it for all those benefits (other than the erections) one little 5mg pill once a day. I could not find any research or reasons to not be taking it.

 

[Guided_by_Voices]

Yes, there is another thread on it here about it, but it seems like a must-do to me. I have pointed out many times that the PDEi5 family is vastly superior to statins for heart health. You might also want to try Nitric Oxide lozenges ( I use n1o1) and something in the growth hormone family depending on your goals.

 

[radman]

I am 67 and gave testosterone a shot earlier this year. I tried both shots and creams. Yes they raised my levels but I did not feel any better. In fact I felt worse. I saw a lot of posts here saying just to give it time, but I gave up on giving it time. I felt testosterone was a younger mans game, and it gets very confusing. I just want to keep things simple so I started researching low dost tadalifil (cialis) There are a lot of articles that say pretty much all men over 40 should be taking it for its prostate, heart, brain protection alone. There are very little if no side effects. Its cheap, and for me it works. I cant say for sure whether or not it is protecting my heart and brain, but I do pee more and wake up in the middle of the night/morning, pretty much every day with erections, and that had not happened in years. Even women can take it for all those benefits (other than the erections) one little 5mg pill once a day. I could not find any research or reasons to not be taking it.

Testosterone and Tadalafil are helpful for different things. For example, testosterone will typically worsen BPH symptoms, while Tadalafil will markedly improve them. And obviously Tadalafil will improve erections, while Testosterone may or may not. Typically the cause of ED in older men is atherosclerosis of the arteries supplying the penis, causing reduced blood flow. Tadalafil improves the blood flow and alleviates the ED. Testosterone does not do this. However, less frequently, ED is related to low libido and associated sexual dysfunction, rather than specifically an problem with blood supply. In these cases, testosterone can help ED, but again this is a much less common cause and therefore testosterone is much less reliable as a treatment for ED. Effects on body composition, fat mass, muscle mass, etc. will be improved with Testosterone and not necessarily with Tadalafil. So to an extent it is apples and oranges, and it depends on what you need to treat, what your underlying medical condition is, etc.
Having said all that, the possibility of broader benefits from daily tadalafil is exciting, though unproven. It has been proven to improve ED and BPH. It has not been proven, despite some preliminary evidence, to reduce risk of cardiovascular disease and dementia/Alzheimers. However, this evidence is tentative because it is simply correlations found in the epidemiological data, and these correlations most of the time don't pan out to be causation. For example, imagine if you looked at a large sample of men that happened to be taking daily tadalafil for ED or BPH, and found that statistically those men had less heart attacks or dementia compared to similar aged men who don't take tadalafil. It doesn't take much thinking to realize that these two groups are not very similar. Men with a lot of chronic health problems, such as pre-existing heart disease, obesity, Diabetes, cancer, etc. are much less likely to be taking daily tadalafil then healthy men of a similar age. The really sick guys are probably not having sex. And they are more likely to die or have Alzheimers. It may just be a confounder. Until randomized trials are preformed, we won't know whether the purported broader benefits to daily tadalafil are real or not. And since it is generic, the funding for large randomized trials will be limited, so it is not clear we will get an answer.

 

[stickersteve]

Testosterone and Tadalafil are helpful for different things. For example, testosterone will typically worsen BPH symptoms, while Tadalafil will markedly improve them. And obviously Tadalafil will improve erections, while Testosterone may or may not. Typically the cause of ED in older men is atherosclerosis of the arteries supplying the penis, causing reduced blood flow. Tadalafil improves the blood flow and alleviates the ED. Testosterone does not do this. However, less frequently, ED is related to low libido and associated sexual dysfunction, rather than specifically an problem with blood supply. In these cases, testosterone can help ED, but again this is a much less common cause and therefore testosterone is much less reliable as a treatment for ED. Effects on body composition, fat mass, muscle mass, etc. will be improved with Testosterone and not necessarily with Tadalafil. So to an extent it is apples and oranges, and it depends on what you need to treat, what your underlying medical condition is, etc.
Having said all that, the possibility of broader benefits from daily tadalafil is exciting, though unproven. It has been proven to improve ED and BPH. It has not been proven, despite some preliminary evidence, to reduce risk of cardiovascular disease and dementia/Alzheimers. However, this evidence is tentative because it is simply correlations found in the epidemiological data, and these correlations most of the time don't pan out to be causation. For example, imagine if you looked at a large sample of men that happened to be taking daily tadalafil for ED or BPH, and found that statistically those men had less heart attacks or dementia compared to similar aged men who don't take tadalafil. It doesn't take much thinking to realize that these two groups are not very similar. Men with a lot of chronic health problems, such as pre-existing heart disease, obesity, Diabetes, cancer, etc. are much less likely to be taking daily tadalafil then healthy men of a similar age. The really sick guys are probably not having sex. And they are more likely to die or have Alzheimers. It may just be a confounder. Until randomized trials are preformed, we won't know whether the purported broader benefits to daily tadalafil are real or not. And since it is generic, the funding for large randomized trials will be limited, so it is not clear we will get an answer.

I agree. I am not having sex at this point anyhow unless I feel like paying for it, but if the opportunity does arise, I am pretty sure I will put on a good show

 

[Willyt]

Yes, there is another thread on it here about it, but it seems like a must-do to me. I have pointed out many times that the PDEi5 family is vastly superior to statins for heart health. You might also want to try Nitric Oxide lozenges ( I use n1o1) and something in the growth hormone family depending on your goals.

Are you taking the Nitric Oxide lozenges with the tadalafil?

 

[stickersteve]

Are you taking the Nitric Oxide lozenges with the tadalafil?

Not yet. I have one of those hydrogen water generator bottles. not sure how the lozenges will help?

 

[Guided_by_Voices]

Are you taking the Nitric Oxide lozenges with the tadalafil?

Yes, although I don't take the NO every day.

 

[Guided_by_Voices]

Not yet. I have one of those hydrogen water generator bottles. not sure how the lozenges will help?

Hydrogen and NO are different things. Cialis works by delaying the breakdown of NO, so having more NO is desirable with or without cialis.

 

[Guided_by_Voices]

Testosterone and Tadalafil are helpful for different things. For example, testosterone will typically worsen BPH symptoms, while Tadalafil will markedly improve them. And obviously Tadalafil will improve erections, while Testosterone may or may not. Typically the cause of ED in older men is atherosclerosis of the arteries supplying the penis, causing reduced blood flow. Tadalafil improves the blood flow and alleviates the ED. Testosterone does not do this. However, less frequently, ED is related to low libido and associated sexual dysfunction, rather than specifically an problem with blood supply. In these cases, testosterone can help ED, but again this is a much less common cause and therefore testosterone is much less reliable as a treatment for ED. Effects on body composition, fat mass, muscle mass, etc. will be improved with Testosterone and not necessarily with Tadalafil. So to an extent it is apples and oranges, and it depends on what you need to treat, what your underlying medical condition is, etc.
Having said all that, the possibility of broader benefits from daily tadalafil is exciting, though unproven. It has been proven to improve ED and BPH. It has not been proven, despite some preliminary evidence, to reduce risk of cardiovascular disease and dementia/Alzheimers. However, this evidence is tentative because it is simply correlations found in the epidemiological data, and these correlations most of the time don't pan out to be causation. For example, imagine if you looked at a large sample of men that happened to be taking daily tadalafil for ED or BPH, and found that statistically those men had less heart attacks or dementia compared to similar aged men who don't take tadalafil. It doesn't take much thinking to realize that these two groups are not very similar. Men with a lot of chronic health problems, such as pre-existing heart disease, obesity, Diabetes, cancer, etc. are much less likely to be taking daily tadalafil then healthy men of a similar age. The really sick guys are probably not having sex. And they are more likely to die or have Alzheimers. It may just be a confounder. Until randomized trials are preformed, we won't know whether the purported broader benefits to daily tadalafil are real or not. And since it is generic, the funding for large randomized trials will be limited, so it is not clear we will get an answer.

IMO we don't need any more "proof" than we already have. There seems to be no argument that NO is positive for the CV system in normal amounts, and PDE5i's indirectly increase it by delaying it's breakdown. Decisions are about risk/reward and cost/benefit, and the PDE5i's are some of the most benign compounds there are, so if they should in theory help and are at least correlated with benefit, then that's good enough for me. Needless to say, there are many other heart-healthy things one should be doing which will also protect NO.

 

[FunkOdyssey]

However, this evidence is tentative because it is simply correlations found in the epidemiological data, and these correlations most of the time don't pan out to be causation.

I thought this too, until I found evidence that tadalafil is substantially more protective than sildenafil. This seems consistent with it's longer half life, supporting the hypothesis that these medications are actually beneficial. Unless of course, you can think of a reason the populations of men prescribed sildenafil vs tadalafil would be meaningfully, relevantly different.

 

[Guided_by_Voices]

I thought this too, until I found evidence that tadalafil is substantially more protective than sildenafil. This seems consistent with it's longer half life, supporting the hypothesis that these medications are actually beneficial. Unless of course, you can think of a reason the populations of men prescribed sildenafil vs tadalafil would be meaningfully, relevantly different.

Great point, and I'm struggling to remember any correlation in the health world that was supported by at least one mechanism, that didn't turn out to be (at least partially) causation.

Correction: I should have said "valid mechanism". Healthy user effected generated invalid correlations and a mechanism was assumed (e.g. saturated fat is bad) however those mechanisms turned out to be mostly wrong. If NO turns out to not be cardio-protective, then the apparent effect of cialis could be called into question, however even so, it appears to be very low risk (unlike statins for example) so the downside should be very low.

 

[jayt]

I am 67 and gave testosterone a shot earlier this year. I tried both shots and creams. Yes they raised my levels but I did not feel any better. In fact I felt worse. I saw a lot of posts here saying just to give it time, but I gave up on giving it time. I felt testosterone was a younger mans game, and it gets very confusing. I just want to keep things simple so I started researching low dost tadalifil (cialis) There are a lot of articles that say pretty much all men over 40 should be taking it for its prostate, heart, brain protection alone. There are very little if no side effects. Its cheap, and for me it works. I cant say for sure whether or not it is protecting my heart and brain, but I do pee more and wake up in the middle of the night/morning, pretty much every day with erections, and that had not happened in years. Even women can take it for all those benefits (other than the erections) one little 5mg pill once a day. I could not find any research or reasons to not be taking it.

I take 5mg Cialis daily and I feel pretty good, notice a big difference with my woody in the morning but on thei nights I know it is about to be a sure thing I take an additional 5mg. I also use injectible trimix.... it guarantees a rock hard penis and depending upon the dose I take, can last 2 or more rounds. When you begin to use trimix you will quickly be able to gage the dose for how long you want to be hard.... for me 20 units on the needle keep me going for 45 minutes to an hour.... most nights I take 40 units and last 2 hours or more depending upon how many times I bust..... my wife is very satisfied and orgasms with me .....