New to TRT. Received first labs. Concerned and need help.

[Phil Goodman]

There's this pervasive myth that 100 mg of testosterone cypionate per week is a low dose. It's not. Top-of-range natural production is equivalent to more like 90 mg TC per week. Typical production in healthy young men is equivalent to 50-70 mg TC per week. Thus you are taking more testosterone than almost any man could make naturally and yet perceive it to be low. There is no evidence that such supraphysiological dosing is better for overall health, and plenty to the contrary.

I agree with a lot of your post, but not sure why you continue to make this specific claim. I’ve provided TONS of evidence that 100-120/week provides a lot more benefits than 50-75/week with very minimal increase in risks(if any increase at all). You’ve provided ZERO evidence that 50-75 mg/week provides comparable benefits, or even that it is particularly safer.


- 100 mg/week is not an absurd starting dose, regardless of how many times you say it is


- if OP ran that protocol for a while and saw benefits with regard to energy, motivation, or other mental aspects then the two most likely explanations (in order) are that the root cause wasn’t testosterone issues all along, which you alluded to …. Or 2.) he hasn’t given his body enough time to fully adjust, as the full spectrum of benefits can take 6-12 months or even longer to fully emerge. The likelihood that he never saw any benefits on those fronts because his starting dose was too high is unlikely. Sure running excessive doses for extended periods of time can cause issues, but getting a huge bump in dopamine and other things while seeing no benefits on the mental front even during the honeymoon phase doesn’t point to an excessive dose imo. It most likely points to one of the other two things I mentioned earlier, or a combination of various other factors.


The only other thing I disagree with in your post, is that I would say people should be more careful tinkering with various neuromodulators like dopamine. You do a good job of pointing of the complexities when it comes to hormones, but I’d say the neuromodulators can be as tricky or even more so with regard to messing around with them and finding a good protocol.