22 yr Old Low E2, 0 Libido

spazak02

New Member
Hi Everyone,

My endo recently started me on TRT - 75 mgs Test E every 5 days after finding a pituitary microadenoma causing low T. Before starting I had the whole cocktail of issues - depression, fatigue, 0 libido, ED, Restrictive eating, Binge eating, Finding no pleasure in anything.

I am a 22 year old male 6'0 170lbs very fit - lean but not excessively lean. I have always been very fit and healthy - my mom is a personal trainer and nutritionist and I have always been interested in nutrition and well being and have worked to get that side optimized. Before my symptoms started ( ~4 years ago) I was a normal teenage boy - boundless energy, libido, etc. Nothing wrong. Since then my issues have worsened over time.

Fast forward to today. 6 weeks ago I finally mustered up the strength to do something about my misery and pressed my endocrinologist to do the MRI which detected the pituitary micro adenoma. Before that I had been taking 25mgs clomid daily which did nothing really. (Oh also should mention I banked sperm so fertility isn't really a concern).

Anyway, I recently did bloodwork and everything looks great except for my E2 which is relatively quite low. I have felt increased energy and improved mood since starting TRT (5 weeks ago) but I still have a complete lack of libido and very flat emotions. I haven't cried in years. And I have had things I definitely should have cried about.

Here is my bloodwork:

Total T - 1,172 ng/dl (Normal range: 317 - 1,234 NG/DL)
Free T - 209.3 pg/ml (Normal range: 48.2 - 169.6 PG/ML)
Bioavailable T - 555.9 ng/dl (Normal range: 113.1 - 397.7 NG/DL)
SHBG - 50.8 nmol/l (Normal range: 14.4 - 90.4 NMOL/L)
Ultrasensitive Estradiol LC MS - 12.7 pg/ml (Normal range: 10.0 - 42.0 pg/mL)
Free T LC-MS/MS - 173.3 pg/ml (Normal range: 47.0 - 244.0 pg/mL)
5-a-Dihydrotestosterone, LC-MS/MS - 428.8 pg/ml (Normal range: 106.0 - 719.0 pg/mL)


I suspect my low E2 is causing my emotional flatness and lack of libido? I am not taking an AI and never have. I would really like to get my libido back. I am about to graduate college and had 0 libido for all 4 years.

If you all think E2 is my issue what can I do elevate it? Is taking oral Estrodial Valerate a good idea? My Endo said she does not want to increase my T dose as my levels are quite high already - and I agree.

Thanks in advance!
 

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