Low cortisol and low testosterone

I’m not sure if it’s fixed but when I switched to enanthate my AM blood cortisol went back to averaging around 12-15.

i tried hydrocortisone in the past and I never felt right on it. I tried doses as low as 5mg per day all the way to 40mg.

my saliva tests still come back low normal first two readings and low last two but I don’t feel to bad nowadays. My only issues now are weird headaches and depression on trt. I’ve been messing around way too much with cream and injections. Having a lot of trouble sticking to one or the other. The cream brings great erections and libido. But overall I feel tired and unmotivated. And injections I feel better playing sports (ice hockey) but I get worse headaches and feel almost allergic to them. I get watery itchy eyes, eye lids and sides of my nose. if I could just feel more stable on cream I would say it’s better overall but sometimes I feel like my t might be too high and others it feels low. I really need to get labs soon and see what’s going on.

I’m also thinking about going back on super low dose of lexapro. I know ssri have a bad reputation but I believe I felt much better mentally in trt with them. I haven’t felt right since I came off almost 3 years ago. it’s progressively getting worse. But I always worry about the long term sides of ssri. I didn’t really have any noticeable sides on the 2.5 mg I was taking a day.
I was curious to ask you what was the maximum length of time you used hydrocortisone the times you tried it
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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