e2 effect on testicular size?

jessie02

New Member
Hey guys! my current protocol is .2ml test EOD and 500iu HCG 2x per week and no AI. Without any reason I can think of my boys seem either high and tight and other times they hang nice they way I like them lol. It can vary from week to week. Without HCG they definitely start to get sore and atrophy more. I thought I read at some point that e2 can have an affect on that. Any input would be great.
 
Hey guys! my current protocol is .2ml test EOD and 500iu HCG 2x per week and no AI. Without any reason I can think of my boys seem either high and tight and other times they hang nice they way I like them lol. It can vary from week to week. Without HCG they definitely start to get sore and atrophy more. I thought I read at some point that e2 can have an affect on that. Any input would be great.
Mine hung very high and very tight only WITH hcg.

Without hcg, they’re smaller than normal but definitely not almonds and I no longer have cold water balls lol.

Been off hcg for years btw.
 
Mine hung very high and very tight only WITH hcg.

Without hcg, they’re smaller than normal but definitely not almonds and I no longer have cold water balls lol.

Been off hcg for years btw.
That's interesting... I think I may have seen you mention this in another post. I guess I could always try and stop for a bit. It makes me wonder if the rise of e2 with the addition of HCG does have an affect...
 
That's interesting... I think I may have seen you mention this in another post. I guess I could always try and stop for a bit. It makes me wonder if the rise of e2 with the addition of HCG does have an affect...

There was a member here a few years back who was convinced of that. In my case, it seems very likely that it had something to do with HCG but I can't necessarily blame it on E2. Recently my E2 got higher than it's ever been (no HCG) and I did not have that issue.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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