Help keeping e2 up

On Amazon...search for "Bio Labs Pro Estrogen". They have a Bi-est cream with estriol and estradiol. An even better place is probably us.onasnatural.com which has a higher concentration of 1mg estradiol per pump in their estrogen cream.

I only used it for 2-3 days at a time, when I overdid anastrozole. I never had to worry about long-term dosing, as I only used it to fix the immediate issue. I couldn't give advice on how much to use for your intended purpose, especially since transdermal absorbtion can vary so much between individuals. You'd have to use the tried and true start low, go slow, analyze labs and monitor any symptoms.
It worked to relieve your crashed e2 symptoms though?
 
Thanks. I added HCG which has fixed my issue for now. I’m back to feeling great. I’m worried about long term sourcing of HCG though.

Sites like reliablerx should be able to get HCG indefinitely. Sites like that get pharma grade HCG from places that it’s legal to just go into the pharmacy and buy it without a prescription, as far as I know. It should always be legal to sell pharma grade HCG
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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