LabCorp 4-Tube Saliva Cortisol-- ideal timing?

eyeheartny

Active Member
My primary care doc RXd some labs for me so my insurance would cover them. I will be sharing the results with Defy but am not sure I'm going to continue working with Defy (long story).

One of them is the LabCorp 4-tube saliva cortisol test. I have the test kit, but it specifies doing it over consecutive days. I want to do all 4 samples on one day in order to map my cortisol pattern throughout the day. What is the optimal timing for the samples in terms of when during the day to take them?

Thanks!
 
My primary care doc RXd some labs for me so my insurance would cover them. I will be sharing the results with Defy but am not sure I'm going to continue working with Defy (long story).

One of them is the LabCorp 4-tube saliva cortisol test. I have the test kit, but it specifies doing it over consecutive days. I want to do all 4 samples on one day in order to map my cortisol pattern throughout the day. What is the optimal timing for the samples in terms of when during the day to take them?

Thanks!

If LabCorp has it listed for four consecutive days they are wrong. All 4 should be drawn on the same day: sample 1 upon waking, sample 2 typically around 12-1PM, sample 3 around 4-5PM, and sample 4 close to bedtime.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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