*UPDATE* New 6 week labs....lowered dose...higher E2!?!?!?

I don’t know what my e2 is right now. I have only been with defy for around 8 weeks and would need to wait for my next labs. I suspect my e2 is probably slightly higher than usual for me. As one of the guys that had tried 3mg/wk of arimidex, .25mg/wk is quite mild for me.
 
So...just a quick update. Had my consultation with Defy. Changing my T dose and injections from 60mg every 3.5 days to M-W-F and dose will start at 40mg on those days and work my way up based on feeling and labs to 50mg three times a week.

Hopefully this will bring down the high E2.

If not, we discussed a exit protocol.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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