What are your experiences with PT-141? (as an aphrodisiac)

[schismz]

How bad is the nauseau for you? Just mild or are you actually vomiting?

Very mild, no vomiting. Nothing dramatic.

 

[GeauxBears]

Wow! I'm going to have to try this! I'm lucky if I can have sex twice a week. I can get erect, but no amount of stimulation brings on an orgasm or ejaculation.

Are you on an AI? I've typically found that lake of orgasm is typically due to reduced penile sensitivity, primarily due to E2 that's too low relative to your T levels.

 

[Ozzieville]

The slight nausea with PT-141 is trivial in my experience - very transitory. The harder (no pun intended) aspect for me with PT-141 is the uncertain timing of onset.

Trimix is a superior option, in my experience. There's no uncertainty about timing: 5 minutes later, and you're ready to go. Trimix doesn't directly affect libido, but funny how having a boner leads to desire for sex, not just vice-versa. Hat tip to Nelson for coaching me on Trimix use.

 

[RickD]

Anyone know where I can get Tri-Mix in Ontario Canada other than through a prescription? I have an appointment with a doc to "teach me" how to inject it but it January next year!!!

 

[RickD]

Are you on an AI? I've typically found that lake of orgasm is typically due to reduced penile sensitivity, primarily due to E2 that's too low relative to your T levels.

I'm much more sensitive that I used to be and it does take me a long time and occasionally, I get tired of fucking before I get there...lol... But the ladies don't seem to mind! lol

 

[RickD]

Very mild, no vomiting. Nothing dramatic.

What dose are you taking?

 

[Techguy]

Thread's been around a while, but wanted to add that my experience was very similar to what @schismz said but different doses. For me 0.5 and 1.0 mg didn't do much except cause long and hard nocturnal erections. For me 1.5 was perfect. No nausea, but did have noticeable flushing about 20 min after injecting and lasting for about 2 hours. In all cases, the peak effect started around 7 hours after injecting. I injected 1.5 mg at 2pm, and from 9pm until midnight before going to sleep just thinking about sex or any mild stimulation triggered a rock hard and long lasting erection. It didn't really effect libido, but getting rock hard definitely puts you in the mood, so looking forward to trying it out with the gf. Initially I was a little concerned about priapism because I was literally hard all night. However, it woke me up every few hours, and using the bathroom every 3-4 hours would cause it to go down. I wouldn't use this more than once a week or preferably every other week. I have always had performance anxiety the first time with a new woman, and while viagra almost does the job, I've found that it doesn't take much stress to emit enough cortisol or adrenaline to defeat the viagra. But the way pt-141 acts centrally, I'm not concerned. There was a study where guys used low dose pt-141 intranasal combined with sildenafil and got good results. I was thinking I might try that for performance anxiety but the 1.5 mg was so strong (for me) that I'd be afraid of priapism if I added anything else!

 

[Rnor143]

What about for girls ?

 

[DorianGray]

What about for girls ?

That is who it was originally produced for. Google Vyleesi. It is the pharmaceutical version of PT-141. With a prescription, women can get a huge discount on the product. If I could get Vyleesi, I wouldn't bother with the knock-off PT-141.

 

[MIP1950]

Hi, so

1. Yes, I can get erect, have sex, orgasm, 2-3 times (sometimes 4 during a 6-8 hour period. I'm on wife 2.0 who is a lot younger than I am FWIW, so I'm married to porn and have lots of motivation. Does your partner think it's fun and is having a good time? If yes, PT-141 kind of keeps you in that zone and enjoying it/able to perform.

2. I do still use it, but never more than 1x a week, for maximum effect I only use it every 10-14 days or so. When I was using it 2-3 times a week I found that I get desensitized and it doesn't last. So for me personally, my rule is, not more than 1x a week, preferably once every 2 weeks just have an awesome sex day

3. I don't buy it online, I have a script for it to obtain from compounding pharmacy, but it's the kind of RX which is more like, "I'd like an RX for this" and my clinician says, "Okay, sure." and if you read the available literature I believe max dose is 4mg.

I don't know if 3mg is "a ton" I just know what I wrote: titrating upwards, 500mcg did nothing for me. And the 1.5mg-2mg doses did "something" but that something was give me nocturnal erections which weren't too terribly helpful or my desired goal.

Over 2.5mg "works" and 3mg is my personal sweet spot to attain the results above. You should see what works for you, since that's the only important variable.

4. Nope. No sides. I do get nausea at about 10 minutes as noted, but it's manageable and not something highly dramatic.

I wrote all this out because I remember learning about PT-141, reading the threads here, trying the advice, and then becoming frustrated that it did nothing at all for me, until I experimented with it a bit.



^^^ that's totally not me. The microdoses did absolutely nothing for me. <shrug> Also, what are you talking about? So far as I know PT-141 is available for injection (what I'm doing) and nasal spray (which I haven't tried yet). There's a oral that works?

Cheers

Your statement about having a wife who likes to have fun(in bed) is highly relevant. Since she's years younger, much more responsive and open. I had an rx for PT-141 and never ordered it from Empower because I wondered if it would make any difference with my sexually indifferent wife. Thinking about Trimix but, again, don't know if her seeing me super hard would turn her on or upset her. Extremely frustrated.

 

[MIP1950]

Anyone know where I can get Tri-Mix in Ontario Canada other than through a prescription? I have an appointment with a doc to "teach me" how to inject it but it January next year!!!

The downside of national healthcare and I'm a supporter of it. Rationing out appointments to specialists or only having a few and they're booked for months or a year. I talk with people in the UK on another forum and that's what they have to contend with. I've experienced that, here, when I wanted to see a psychiatrist who specializes in thyroid and mood disorders. Six month waiting list and $600. Doesn't take insurance. Never saw him.

 

[Anonymon]

I ordered a couple of bottles of PT-141 and will be trying it out in a week or two. I can get most of my protocol great, but that typically results in a complete lack of penile sensation, which breaks my dick. Be nice if I could use this as a fall back while I’m playing around with things.

 

[Esq]

I ordered a couple of bottles of PT-141 and will be trying it out in a week or two. I can get most of my protocol great, but that typically results in a complete lack of penile sensation, which breaks my dick. Be nice if I could use this as a fall back while I’m playing around with things.

Have you checked your prolactin levels? I was struggling with a lack of penile sensitivity and difficulty reaching orgasm. I tried PT-141 first and couldn't handle the sides. It gave my insane erections and helped a bit with the sensitivity issues, but then I'd suffer from flu-like symptoms, including full body ache, for a day or two after. It just wasn't worth it.

My TRT doc tested prolactin, and it turns out mine was very elevated. He prescribed a low dose of cabergoline, which has helped immensely.

 

[Anonymon]

Have you checked your prolactin levels? I was struggling with a lack of penile sensitivity and difficulty reaching orgasm. I tried PT-141 first and couldn't handle the sides. It gave my insane erections and helped a bit with the sensitivity issues, but then I'd suffer from flu-like symptoms, including full body ache, for a day or two after. It just wasn't worth it.

My TRT doc tested prolactin, and it turns out mine was very elevated. He prescribed a low dose of cabergoline, which has helped immensely.

Not since the issues started. For me, they’re caused by the T3 I take. Adding in T4 at night helps, but causes massive hair shedding typically. Unfortunately, I haven’t been able to get around my need for T3.

 

[AustinLakeSnake]

I tried it 3 times working up from 5 units to 10 units to 15. First time, nothing. Second time I had some spontaneous erections. Third time nausea with vomiting and spontaneous erections. It took several hours for it to kick in.

After the vomiting episode, not sure if I want to try it again. I've never tried it, but would prefer to try Trimix or Bimix before I do PT-141 again.

I switched from primarily using Cialis to Viagra and that seemed to work better. I think your body builds a resistance after long use.

Tri-mix is da bomb!

 

[AustinLakeSnake]

The slight nausea with PT-141 is trivial in my experience - very transitory. The harder (no pun intended) aspect for me with PT-141 is the uncertain timing of onset.

Trimix is a superior option, in my experience. There's no uncertainty about timing: 5 minutes later, and you're ready to go. Trimix doesn't directly affect libido, but funny how having a boner leads to desire for sex, not just vice-versa. Hat tip to Nelson for coaching me on Trimix use.

PT 141 gave me an incredibly hard erection for hours but took 45 minutes to set in and was accompanied by nausea. Trimix takes 10 minutes to set in and lasts for as long as I want (a few times longer, lol). The pt 141 erection was superior in that it felt more sexual, but the nausea ruined it.