Is it possible to block the vasodilatory effect of testosterone?

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readalot

Member
I'm on a TRT dose not supraphysiological.
This is a common theme we debate on here....the critical question is whether the serum levels you are running currently supraphysiologic for you?

You mention 300 ng/dl after you took something you shouldn't have, but do you have your baseline prior to that? Usually it is hard to know whether the physiologic ref range for male population (say 300-1200 ng/dl) is applicable as physiologic to a particular individual.
 
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transetpmedia

New Member
This is a common theme we debate on here....the critical question is whether the serum levels you are running currently supraphysiologic for you?

You mention 300 ng/dl after you took something you shouldn't have, but do you have your baseline prior to that? Usually it is hard to know whether the physiologic ref range for male population (say 300-1200 ng/dl) is applicable as physiologic to a particular individual.
Ah OK I get you. I would say I don't think so, just because I have had these heart symptoms for around 7/8 years now, although they probably got a little bit worse over time (which is worrying). So regardless of TRT or not I get these symptoms from other things, and because many things cause it then it isn't surprising that TRT is having an effect.
 

readalot

Member
Ah OK I get you. I would say I don't think so, just because I have had these heart symptoms for around 7/8 years now, although they probably got a little bit worse over time (which is worrying). So regardless of TRT or not I get these symptoms from other things, and because many things cause it then it isn't surprising that TRT is having an effect.
Gotcha, thanks. So exogenous T use seems to be exacerbating the issue. With COVID, TRT, lifestyle, workouts, I don't know up from down most days!

I wish you well and hope you figure it out. I would definitely seek the opinion of hematologist. I've seen many where Hct goes up and some that can't support Hct via iron metabolism. Check you CBC and consider a hematology consult?
 

sammmy

Active Member
Ok, so have you used it yourself for a similar reason? Does it interfere with sleep in your experience?
I get "pounding pulse" and severe fatigue/dizziness/headaches after meals, but I have a low blood pressure and it dips even lower after meals. What helps me with those is 15mg pseudoephedrine - got it with prescription in US, a nasal decongestant by Sunmark, no caffeine in it.

I don't like caffeine - exacerbates the post meal palpitations and doesn't help with the headaches or fatigue.

Surprisingly, a low dose aspirin 81mg also helps me - it suppresses the post meal palpitations and unpleasant feeling in my head and removes the fatigue even better than pseudoephedrine. If aspirin didn't have negative effect on kidneys and intestines, probably I would take aspirin daily.
 

sammmy

Active Member
I haven't noticed 15-30mg pseudoephedrine taken at noon to interfere with sleep at night. I am on a sleep medication zolpidem/Ambien and am very sensitive to stimulants.

Herbal stimulants such as reg ginseng, guarana, herbal ephedra impair my sleep even if I take them at noon, probably because they are complex mixtures not pure compounds that are metabolized in a few hours.
 

TorontoTRT

Active Member
Seems like you keep messing with your protocol and not allowing for any long term stabilizing effects. Pick a dose and stick with it for a full 6 months or more. Your current dose is low, keeping you at mid normal levels. Hence it’s not trt causing issues, and your pulse issue sounds like anxiety. Since all tests show it’s nothing else.
 

Fortunate

Active Member
1. What other medications are you taking, including supplements? Anything at all?
2. Have you had your thyroid levels checked?
3. Consider a trial of Natesto. It might address whatever low T symptoms you were having without the side effects you describe.
 
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