Considering TRT for Accutane related hormonal changes

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FunkOdyssey

Well-Known Member
Does your acne come back now on TRT?

At 70 mg weekly, my skin was perfectly clear and smoother than pre-TRT which was shocking to me. Since I increased to 105 mg weekly, my skin is slightly worse and about the same as pre-TRT. My levels are still increasing though and minor acne might be a result of the fluctuation in levels and not the levels themselves. From my experience so far, it seems like I would need to get my levels cranked up really high in order to get any significant acne.

I should mention that injecting subcutaneously caused an immediate and severe eruption of acne. I won't make that mistake again. My reaction was so negative that after two subq shots I gave up on TRT until my provider convinced me to try IM instead.
 
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Frizzle

Member
At 70 mg weekly, my skin was perfectly clear and smoother than pre-TRT which was shocking to me. Since I increased to 105 mg weekly, my skin is slightly worse and about the same as pre-TRT. My levels are still increasing though and minor acne might be a result of the fluctuation in levels and not the levels themselves. From my experience so far, it seems like I would need to get my levels cranked up really high in order to get any significant acne.

I should mention that injecting subcutaneously caused an immediate and severe eruption of acne. I won't make that mistake again. My reaction was so negative that after two subq shots I gave up on TRT until my provider convinced me to try IM instead.
Good pointer! do tou know what your serum levels DHT are?
 

FunkOdyssey

Well-Known Member
Good pointer! do tou know what your serum levels DHT are?
Yes, my pre-TRT DHT was 38 ng/dL and that increased to 54 ng/dL at 70 mg weekly. The higher DHT was counterintuitively associated with clearer skin. I will measure again after stabilizing at 105 mg weekly.
 

FunkOdyssey

Well-Known Member
Frizzle said:
Have you tried Boron raise free T? How high are you aiming your DHT?
Now that I'm on TRT there's no reason to take supplements that claim to increase free T. I would just increase my TRT dose.

I don't have a DHT target. I'm only measuring it to see what happens to it at different TRT doses and how it might correlate with benefits or side effects I experience.
 

Mr.63

New Member
I've taken 3 rounds of Accutane in my life and each time I felt my energy levels dwindle a bit more.

Now that I'm on HRT I don't feel good on normal doses (100-150mg test) possibly because of long-lasting 5AR downregulation. I feel like complete crap on those doses.

I need at least 180-200mg to feel good. Interestingly, 150mg testosterone + 35mg masteron takes care of the problem, which further leads me to think DHT is indeed the issue.
At what frequency do you inject 180-200mg?
 

Frizzle

Member
I've taken 3 rounds of Accutane in my life and each time I felt my energy levels dwindle a bit more.

Now that I'm on HRT I don't feel good on normal doses (100-150mg test) possibly because of long-lasting 5AR downregulation. I feel like complete crap on those doses.

I need at least 180-200mg to feel good. Interestingly, 150mg testosterone + 35mg masteron takes care of the problem, which further leads me to think DHT is indeed the issue.
Do you have high / higher SHBG?
 

Mr.63

New Member
What’s your story Mr.63?
I used a ton of AAS starting at 18 years old and acctually never came off. Around 19 i used accutane too wich took care of my acne. I kept blasting and cruising after that but slowly started losing my libido over the years. Not sure if its the accutane or not. By the time i was een 25 i quit all AAS. Stayed off till i was 27-28 but never recovered. Been on trt since but unable to find libido. Had some periods when things were good but always faded away. Im 31 now btw
 

Frizzle

Member
I used a ton of AAS starting at 18 years old and acctually never came off. Around 19 i used accutane too wich took care of my acne. I kept blasting and cruising after that but slowly started losing my libido over the years. Not sure if its the accutane or not. By the time i was een 25 i quit all AAS. Stayed off till i was 27-28 but never recovered. Been on trt since but unable to find libido. Had some periods when things were good but always faded away. Im 31 now btw

What type of TRT do you use? And how much of it? Have your other symptoms resolved with TRT?

Guys that I know who’ve fixed their libido after Accutane are on higher than normal doses TRT.
 

Mr.63

New Member
What type of TRT do you use? And how much of it? Have your other symptoms resolved with TRT?

Guys that I know who’ve fixed their libido after Accutane are on higher than normal doses TRT.
Only thing that has been resolved for me are gym gains. But thats the least important for me. Im still pretty letargic, poor mood i just dont care much at all about things. Excitement of life is juste a bit gone, its hard to explain.

I was once completely dialed in on cream + injections. Everything was great, good mood, got stuff done, amazing libido + rock hard erections, could bang as much as i wanted in 1 day. Then my new batch of cream came in and all was lost. That was a pretty hard slap in my face. I had to search so long for something to work. And then in 2 days with the new batch im back to where i was.

I use injections right now. 10mg daily. This has only been 2 weeks. Have been on different protocols. So im just trying something new. If this doesn’t work im gonna try an cream+ injection protocol again in hope to find something that works.
 

Mr.63

New Member
Good thing you already saw some temporary success. Do you have a competent Dr. to guide/advise/treat you?

They are or were on 180-200mg, different protocols.
No. I live in Belgium. Im lucky to have acces to pharmacy testosterone injections and cream. But unfortunately no competent doctor to treat me.
 

Frizzle

Member
I’m from Holland, so I’m your neighbour. You could contact The Hertoghe clinic in Belgium, Balance my Hormones Europe or The Mens Health Clinic in England.
 
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