Considering Dr. Saya for 2nd try with TRT – any advice appreciated

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Linus

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Short version: mid-50s male, tried TRT six years ago (w/probably a poor protocol) for anxiety/depression/motivation, had some brief, wonderful ‘honeymoon’ effects, but stopped after two weeks due to worsened BPH. I’m now very impressed by what I’ve read of Dr. Saya and considering trying again under his care, but I wonder if my BPH susceptibility makes me ineligible. Further challenges: I seem to be a Cialis non-responder, plus I don’t want to take finasteride.

Long version: While I can’t say I feel “horrible”, I still have mild anxiety and depression, nothing strikes me as fun, I’ve gotten notably more forgetful and “brain foggy”, I have zero interest in sex, and am adding fat and losing muscle. I have a physique that might even be a bit worse than this:

belly.jpg

In fact, I have all of the issues that drove me to try TRT five years ago, but they’ve gradually worsened since then.

BPH: Normally, I have mild but very manageable BPH with adequate but not 'great' urine flow. But it's never bothered me, nor do I feel I have many nighttime trips to the bathroom.

Earlier TRT experience:

About five years ago, I did TRT with someone who prescribed:

Test Cyp 200 @ 26mg/daily injections
1/4mg Anastrazole daily, except ½ mg MWF
HCG (can’t find notes on how much)
100mg pregnenolone daily
30mg DHEA daily

Result: I felt amazing quickly. In fact, the first night I wanted to run wind sprints at 1 am. (I know this will be attributed to a placebo effect, but I wasn’t expecting TRT to work.) That week confidence soared, I was energetic, super attracted to the opposite sex – it was awesome. Yet after just a few days at this dose noticed slowed urination, so my dosage was reduced to 20 mg/day.

But urination was still slow, so I was told to pause for a week. Urination seem to return to baseline, so then I tried again for another week. After a week, urination was again slow, and I had a burning sensation in my scalp that made me fear all my hair would fall out. The last 'straw' for me was when defecating one day, I felt the bowel movement actually pushing my enlarged prostate out of the way as I defecated. I literally had to “push” to get the bowel movement past my prostate. At this point, I was scared I’d have to go to the E.R. at some point to be catheterized to keep my bladder from bursting, so I gave up on TRT. Counting the 'paused' week, my adventure lasted a total of 21 days.

(Recently, I read a post by Dr. Saya where he explained that daily injections can actually have much stronger effect than less frequent injections, so I think this is part of what I experienced.)

As for my scalp, I did wind up losing some hair on the crown and had some recession on the left and right front – basically, like Jude Law’s hair -- but this has gradually happened over the past five years.
jude law.jpg

Present day: Having “bearable” yet steadily worsening symptoms drove me to find this forum. I decided to try again and see if I could find a doctor who was confident that I could be on TRT successfully, despite my BPH.

So late 2016, I scheduled an appointment with a TRT doctor in my town. I was told to get labs done before the appointment, and here they are:

http://i.imgur.com/z1YkZZB.png
lab screenshot half.jpg

I met with the doctor and liked him a lot. But even though I told him my history, my hesitations about Finasteride and emphasized wanting to start slowly, this was the protocol he prescribed:

Test Cyp 200, 1 ml weekly
Anastrazole 1mg EOD
Finasteride 5mg daily

This protocol seemed aggressive to me, especially in the light of my previous experience, but it seems to be this guy's standard protocol. I called back to discuss things with him and was not able to reach him, and instead spoke to a nurse in his office. She told me that I would need the finasteride if I wanted to avoid hairloss and BPH symptoms. When I asked about Cialis as an alternate way of controlling BPH, she noted that Cialis might help the BPH, but would do nothing to control hairloss.

I guess the aggressive protocol, coupled with an inability to reach him after the initial hour consult, created in me a lack of confidence in this guy. He's not cheap, but it all feels a bit "wham, bam, thank you, man" to me.

So when the supplies arrived, I never started, and instead thought about waiting to consult with Dr. Saya.

[By the way, I did test the Cialis, but it seems to have no effect on me. (Viagra works well for me.)]

So I do want to try TRT again, but I’m left with my key fear: Will there be a more gradual or “gentle” TRT protocol I can do (and/or a way of keeping my BPH at bay) without Finasteride so that I can have some of the benefits of TRT? Or are there many men who simply can't do TRT due to BPH?

I'm happy to pay what Dr. Saya costs, and to wait to talk to him, but with my BPH history, is there any point? I'd love to hear advice from other forum members who may have dealt with BPH.

(By the way, I’m kind of amazed by the number of members on this forum with deep knowledge of this subject who are willing to help – this place is really kind of astounding.)
 

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Your in the right place here. I like the fact that you are looking for what is best for you. I'm not educated in BPH or how to overcome this along with TRT but a lot of guys here are. I've read good things about Dr. Saya. When you first started TRT, two weeks is not enough time to reap long term benefits. Your first protocol looked a lot better than what most start at.

I certainly hope you get the help your looking for.
 
Your previous docs had you on a "cookie cutter" protocol with no labs to back-up their huge doses of AI, either. A normal starting T dose is 100 mg a week split into at least 2 doses, HCG at least twice weekly and no AI. Additionally no AI should be added unless its proven to be needed by overt high E2 symptoms or high levels on the Sensitive Assay E2 test.
 
I don't believe your a candidate for TRT. Your thyroid is another issue. Find a good doctor to take care of your hypothyroidism and start living clean.
 
Welcome to Excelmale. You asked if it's worth consulting Dr. Saya given your history, both your medical history and your prior TRT experience. Of course it's worth the time and expense of an initial consultation. Not because I think you're a candidate for TRT, or because I think you're not a candidate for TRT, but because you owe it to yourself to determine what's amiss with your health. Defy isn't a testosterone mill and Dr. Saya doesn't have a quota of patients he must enroll in a protocol every month. He has written here that he is honest with men who don't meet the criteria for TRT; he does, however, works with them to deal with other issues contributing to their health problems. Your androgen labs are not that bad, some of your other numbers are not very good, but I'm not Dr. Saya; call Defy and get a definitive answer.

As for your BPH - stay away from finasteride! Do not run the risk of intractable erectile dysfunction and long-term libido problems. It's a risky drug. We have members who continue to struggle with its effects for some time after they quit taking it.


Has a urologist conducted a comprehensive examination? Urodynamic studies? Was tamsulosin tried? In my case mild BPH was arrested with tamsulosin and testosterone has had a very good effect on some other lower urinary tract symptoms.
 
Thanks to everyone for the comments. They're very appreciated.

CoastWatcher, no, I've not looked into BPH because it hasn't been a problem in normal life. It only became an issue during my earlier TRT experience (and once before, in response to a prescription antihistamine.) I think my anatomy may predispose me to the issue in certain contexts, but not in daily life.
 
Thanks to everyone for the comments. They're very appreciated.

CoastWatcher, no, I've not looked into BPH because it hasn't been a problem in normal life. It only became an issue during my earlier TRT experience (and once before, in response to a prescription antihistamine.) I think my anatomy may predispose me to the issue in certain contexts, but not in daily life.


I'd be surprised if BPH can't be managed. It's a common issue.
 
I don't believe your a candidate for TRT. Your thyroid is another issue. Find a good doctor to take care of your hypothyroidism and start living clean.

Vince, what makes you think his thyroid is an issue? I understand by our knowledgeable standards, that a TSH of 3.6 is on the high side and should be closer to 1.0-1.5. The reality is that MANY doctors will not treat this, especially because his fT4 is in range. Would like to see fT3 however.

My take on this is that you need an extremely knowledgeable urologist. You need to get the BPH under control. I know a few great guys in the NYC area. Clearly, TRT makes you feel great again but it aggravates BPH. The risks do not outweigh the benefits. You need someone who knows about replacement therapy and can manage your BPH... aka a Urologist with a fellowship in Andrology as well. OP, PM me if you would like for doctor(s) in the NYC area.

Edit: Just saw your fT3 at the bottom. My apologies. You do not have hypothyroidism. You have subclinical hypothyroidism. Which usually doesn't give you symptoms, but sometimes will. Your thyroid gland doesn't put out thyroid hormone as efficiently as it should, hence the high TSH. However, you thyroid levels are in a good range. Like I said, many many doctors will not treat this. Only a few would dabble with T4. My original opinion still remains, manage BPH via urologist. Do not use Finasteride. Live a better life style. Start using iodized salt. Then come here to see Dr. Saya for TRT.
 
Beyond Testosterone Book by Nelson Vergel
Short version: mid-50s male, tried TRT six years ago (w/probably a poor protocol) for anxiety/depression/motivation, had some brief, wonderful ‘honeymoon’ effects, but stopped after two weeks due to worsened BPH. I’m now very impressed by what I’ve read of Dr. Saya and considering trying again under his care, but I wonder if my BPH susceptibility makes me ineligible. Further challenges: I seem to be a Cialis non-responder, plus I don’t want to take finasteride.

Long version: While I can’t say I feel “horrible”, I still have mild anxiety and depression, nothing strikes me as fun, I’ve gotten notably more forgetful and “brain foggy”, I have zero interest in sex, and am adding fat and losing muscle. I have a physique that might even be a bit worse than this:

View attachment 3154

In fact, I have all of the issues that drove me to try TRT five years ago, but they’ve gradually worsened since then.

BPH: Normally, I have mild but very manageable BPH with adequate but not 'great' urine flow. But it's never bothered me, nor do I feel I have many nighttime trips to the bathroom.

Earlier TRT experience:

About five years ago, I did TRT with someone who prescribed:

Test Cyp 200 @ 26mg/daily injections
1/4mg Anastrazole daily, except ½ mg MWF
HCG (can’t find notes on how much)
100mg pregnenolone daily
30mg DHEA daily

Result: I felt amazing quickly. In fact, the first night I wanted to run wind sprints at 1 am. (I know this will be attributed to a placebo effect, but I wasn’t expecting TRT to work.) That week confidence soared, I was energetic, super attracted to the opposite sex – it was awesome. Yet after just a few days at this dose noticed slowed urination, so my dosage was reduced to 20 mg/day.

But urination was still slow, so I was told to pause for a week. Urination seem to return to baseline, so then I tried again for another week. After a week, urination was again slow, and I had a burning sensation in my scalp that made me fear all my hair would fall out. The last 'straw' for me was when defecating one day, I felt the bowel movement actually pushing my enlarged prostate out of the way as I defecated. I literally had to “push” to get the bowel movement past my prostate. At this point, I was scared I’d have to go to the E.R. at some point to be catheterized to keep my bladder from bursting, so I gave up on TRT. Counting the 'paused' week, my adventure lasted a total of 21 days.

(Recently, I read a post by Dr. Saya where he explained that daily injections can actually have much stronger effect than less frequent injections, so I think this is part of what I experienced.)

As for my scalp, I did wind up losing some hair on the crown and had some recession on the left and right front – basically, like Jude Law’s hair -- but this has gradually happened over the past five years.
View attachment 3155

Present day: Having “bearable” yet steadily worsening symptoms drove me to find this forum. I decided to try again and see if I could find a doctor who was confident that I could be on TRT successfully, despite my BPH.

So late 2016, I scheduled an appointment with a TRT doctor in my town. I was told to get labs done before the appointment, and here they are:

http://i.imgur.com/z1YkZZB.png
View attachment 3157

I met with the doctor and liked him a lot. But even though I told him my history, my hesitations about Finasteride and emphasized wanting to start slowly, this was the protocol he prescribed:

Test Cyp 200, 1 ml weekly
Anastrazole 1mg EOD
Finasteride 5mg daily

This protocol seemed aggressive to me, especially in the light of my previous experience, but it seems to be this guy's standard protocol. I called back to discuss things with him and was not able to reach him, and instead spoke to a nurse in his office. She told me that I would need the finasteride if I wanted to avoid hairloss and BPH symptoms. When I asked about Cialis as an alternate way of controlling BPH, she noted that Cialis might help the BPH, but would do nothing to control hairloss.

I guess the aggressive protocol, coupled with an inability to reach him after the initial hour consult, created in me a lack of confidence in this guy. He's not cheap, but it all feels a bit "wham, bam, thank you, man" to me.

So when the supplies arrived, I never started, and instead thought about waiting to consult with Dr. Saya.

[By the way, I did test the Cialis, but it seems to have no effect on me. (Viagra works well for me.)]

So I do want to try TRT again, but I’m left with my key fear: Will there be a more gradual or “gentle” TRT protocol I can do (and/or a way of keeping my BPH at bay) without Finasteride so that I can have some of the benefits of TRT? Or are there many men who simply can't do TRT due to BPH?

I'm happy to pay what Dr. Saya costs, and to wait to talk to him, but with my BPH history, is there any point? I'd love to hear advice from other forum members who may have dealt with BPH.

(By the way, I’m kind of amazed by the number of members on this forum with deep knowledge of this subject who are willing to help – this place is really kind of astounding.)
Sir, I would be willing to bet if you focused on thyroid, your problems would go away without the need of TRT. Improving the thyroid will actually raise your testosterone levels. This would also lower your LDL quite a bit.

But it would definitely be worth meeting Saya. I would suggest running more tests to see if it is autoimmune in nature: Hashimotos or celiac.
 
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