When would this protocol be started for someone coming off twice weekly TRT doses?

Stoak

Active Member
I am getting results of a semen analysis and if they are poor, I'm contemplating doing the following after talking to my doctor as one of my options. When would one start this protocol? How long after the last test cyp injections?



The protocol for HPTA normalization contains (edited on Dec 2017):

First 15 days:

HCG 1,000-2,000 IU (subcutaneous) every 3 days;
Clomiphene citrate 25-50 mg orally once a day; and
Tamoxifen 20 mg orally once a day.

A satisfactory testosterone level on day 15, typically 350 ng/mL or greater, is followed by the oral medications (no HCG) for an additional 15 days (25 mg per day clomiphene would be sufficient).
 
I would try 1000 IU HCG twice per week for 4-6 weeks. After the HCG, I would take 25 mg/day of Clomid instead of 50 mg for 4 weeks and 12.5 mg/day for another 4 weeks.
 
I would try 1000 IU HCG twice per week for 4-6 weeks. After the HCG, I would take 25 mg/day of Clomid instead of 50 mg for 4 weeks and 12.5 mg/day for another 4 weeks.
How soon after the last tect cyp inject do I start the protocol?
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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