What Should Men Over 60 Be Aware of When Taking Testosterone?

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Excel Male

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Testosterone
Sep 24, 2011

Well it happened, i was on anti depress, anixety meds, and then my doctoc check my testy, and it was as low as it gets according to doc, went on once a month, then biweekly and raised it to 730 now back to once a month..68 yrs of age, woodys galore, depression gone, muscle up, fat gone..overall feeling better..no side effects from this med and feel much better..i think all older men should get their testy checked..i take maximum dose and does this increase my chances for anything serious..i am type two di and take glipizide, metform, but to keep this lean body and muscle, i'm willing to take the possible severe side effects, any responses??


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Response from Mr. Vergel


Good to hear that you are doing well on testosterone. Testosterone replacement therapy improves insulin response in diabetic patients.
Three warnings for you since you are over 60 years of age (some studies have reported some red flags on testosterone replacement in older men):

1- Make sure that your hematocrit is never over 52. If it is, you need to have 3-4 units of blood drawn every 2-4 months (you should check hematocrit monthly if you have this side effect). High hematocrit can dramatically increase cardiovascular risks.

2- Get your prostatic specific antigen checked every 6 months to ensure that it is OK. If you see a sharp increase, then there may be an issue with prostatic cancer if hidden cancer was present when you started testosterone. An annual digital rectal exam if also advisable.

3- Have your estradiol checked every few months during the first year to ensure it is not much over 30 picograms. High estradiol can cause water retention, mood issues, and increased breast size.

I have provided detailed information on these issues in Testosterone: A Man's Guide

I think that men who start testosterone without reading about potential side effects and how to manage them are a little naive. Yes, your doctor should be looking out for you, but many doctors are too busy and may not be following guidelines. I hope this email did not bring you down from your excitement. Many men have the benefits you report without side effects. But the only way to find out early if you are one of those lucky ones is to follow the advise that I provided here. Short term benefits are great but not at the expense of long term problems.

Nelson
 
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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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