What Doctors Got WRONG About Testosterone and Prostate Cancer

madman

Super Moderator

In this episode, Dr. Morgentaler and Dr. Brandon unpack the myth that eunuchs never get prostate cancer and reveal how powerful stories—not science—shaped decades of medical belief about testosterone.




00:07The Story of Testosterone and Prostate Cancer

In this episode, Dr. Morgentaler and Dr. Brandon talk about how the belief that testosterone causes prostate cancer became so widely accepted—even without real evidence.


01:52Understanding Eunuchs and Historical Context

They explain who eunuchs were and how their story got tied to prostate cancer in a way that stuck for decades.


05:43The Castrati and Misconceptions

Dr. Morgentaler shares how the story of the castrati singers was used to support a medical myth, even though there was no real data behind it.


06:56 Modern Research and Findings

They walk through what today’s research actually shows, including cases where people with little or no testosterone still developed prostate cancer.



14:19 Conclusions and Reflections

They wrap up by reminding us how powerful stories can shape beliefs—even in medicine—and why it’s so important to keep questioning what we think we know.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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